Sarepta Therapeutics, Inc.
MX ˙ BMV ˙ US8036071004
SecurityMX:SRPT / Sarepta Therapeutics, Inc.
InstitutionFirst Trust Advisors Lp
Latest Disclosed Ownership4,135,788 shares
Latest Disclosed Value $ 89,994,703
First Trust Advisors Lp reports 107.56% increase in ownership of SRPT / Sarepta Therapeutics, Inc.

On May 13, 2026 - First Trust Advisors Lp filed a 13F-HR form disclosing ownership of 4,135,788 shares of Sarepta Therapeutics, Inc. (MX:SRPT) valued at $89,994,703 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 1,992,577 shares of Sarepta Therapeutics, Inc.. This represents a change in shares of 107.56% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F SAREPTA THERAPEUTICS COM 803607100 4,135,788 2,143,211 107.56 89,995 109.87 0.0641
2026-02-13 2025-12-31 13F SAREPTA THERAPEUTICS COM 803607100 1,992,577 52,796 2.72 42,880 14.72
2025-11-12 2025-09-30 13F SAREPTA THERAPEUTICS COM 803607100 1,939,781 1,312,220 209.10 37,380 248.33 0.0278
2025-08-13 2025-06-30 13F SAREPTA THERAPEUTICS COM 803607100 627,561 233,391 59.21 10,731 -57.34 0.0086
2025-05-14 2025-03-31 13F SAREPTA THERAPEUTICS COM 803607100 394,170 82,385 26.42 25,156 -33.64 0.0223
2025-02-13 2024-12-31 13F SAREPTA THERAPEUTICS COM 803607100 311,785 -153,131 -32.94 37,910 -34.71 0.0334
2024-11-13 2024-09-30 13F SAREPTA THERAPEUTICS COM 803607100 464,916 363,000 356.18 58,063 260.59 0.0553
2024-08-13 2024-06-30 13F SAREPTA THERAPEUTICS COM 803607100 101,916 101,916 16,103 0.0164
2024-05-13 2024-03-31 13F SAREPTA THERAPEUTICS COM 803607100 0 -432,350 -100.00 0 -100.00
2024-02-13 2023-12-31 13F SAREPTA THERAPEUTICS COM 803607100 432,350 1,376 0.32 41,691 -20.20 0.0455
2023-11-13 2023-09-30 13F SAREPTA THERAPEUTICS COM 803607100 430,974 -173,362 -28.69 52,243 -24.51 0.0619
2023-08-14 2023-06-30 13F SAREPTA THERAPEUTICS COM 803607100 604,336 -85,276 -12.37 69,209 -27.19 0.0787
2023-05-15 2023-03-31 13F SAREPTA THERAPEUTICS COM 803607100 689,612 -18,334 -2.59 95,049 3.62 0.1098
2023-02-09 2022-12-31 13F SAREPTA THERAPEUTICS COM 803607100 707,946 -209,296 -22.82 91,731 -9.53 0.1091
2022-11-14 2022-09-30 13F SAREPTA THERAPEUTICS COM 803607100 917,242 226,947 32.88 101,391 95.95 0.1315
2022-08-12 2022-06-30 13F SAREPTA THERAPEUTICS COM 803607100 690,295 -169,453 -19.71 51,744 -22.96 0.0639
2022-05-13 2022-03-31 13F SAREPTA THERAPEUTICS COM 803607100 859,748 -39,308 -4.37 67,164 -17.04 0.0687
2022-02-08 2021-12-31 13F SAREPTA THERAPEUTICS COM 803607100 899,056 -30,152 -3.24 80,960 -5.79 0.0788
2021-11-15 2021-09-30 13F SAREPTA THERAPEUTICS COM 803607100 929,208 56,916 6.52 85,933 26.69 0.0924
2021-10-12 2021-06-30 13F/A-1 SAREPTA THERAPEUTICS COM 803607100 872,292 -13,579 -1.53 67,829 2.73 0.0734
2021-08-16 2021-06-30 13F SAREPTA THERAPEUTICS COM 803607100 877,752 -8,119 68,236 0.0704
2021-05-14 2021-03-31 13F SAREPTA THERAPEUTICS COM 803607100 885,871 349,454 65.15 66,024 -27.81 0.0799
2021-02-02 2020-12-31 13F SAREPTA THERAPEUTICS COM 803607100 536,417 -50,749 -8.64 91,454 10.91 0.1212
2020-11-05 2020-09-30 13F SAREPTA THERAPEUTICS COM 803607100 587,166 -81,870 -12.24 82,456 -23.13 0.1321
2020-07-22 2020-06-30 13F SAREPTA THERAPEUTICS COM 803607100 669,036 138,658 26.14 107,273 106.76 0.1859
2020-05-06 2020-03-31 13F SAREPTA THERAPEUTICS COM 803607100 530,378 -68,590 -11.45 51,882 -32.87 0.1175
2020-02-03 2019-12-31 13F SAREPTA THERAPEUTICS COM 803607100 598,968 -70,352 -10.51 77,291 53.32 0.1320
2019-11-04 2019-09-30 13F SAREPTA THERAPEUTICS COM 803607100 669,320 -204,541 -23.41 50,413 -62.03 0.0949
2019-07-30 2019-06-30 13F SAREPTA THERAPEUTICS COM 803607100 873,861 775,458 788.04 132,783 1,032.09 0.2503
2019-06-19 2019-03-31 13F/A-1 SAREPTA THERAPEUTICS COM 803607100 98,403 -277,202 -73.80 11,729 -71.39 0.0233
2019-05-09 2019-03-31 13F SAREPTA THERAPEUTICS COM 803607100 98,403 -277,202 11,729
2019-02-07 2018-12-31 13F SAREPTA THERAPEUTICS COM 803607100 375,605 138,218 58.22 40,990 6.91 0.0972
2018-10-25 2018-09-30 13F SAREPTA THERAPEUTICS COM 803607100 237,387 173,782 273.22 38,340 356.05 0.0714
2018-08-02 2018-06-30 13F SAREPTA THERAPEUTICS COM 803607100 63,605 11,668 22.47 8,407 118.48 0.0174
2018-04-23 2018-03-31 13F SAREPTA THERAPEUTICS COM 803607100 51,937 9,067 21.15 3,848 61.34 0.0088
2018-02-08 2017-12-31 13F SAREPTA THERAPEUTICS COM 803607100 42,870 -14,798 -25.66 2,385 -8.83 0.0057
2017-10-24 2017-09-30 13F SAREPTA THERAPEUTICS COM 803607100 57,668 26,574 85.46 2,616 149.62 0.0067
2017-08-02 2017-06-30 13F SAREPTA THERAPEUTICS COM 803607100 31,094 13,316 74.90 1,048 99.24 0.0028
2017-05-02 2017-03-31 13F SAREPTA THERAPEUTICS COM 803607100 17,778 -10,673 -37.51 526 -32.56 0.0015
2017-02-06 2016-12-31 13F SAREPTA THERAPEUTICS COM 803607100 28,451 28,451 780 0.0023
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.