LOXO Insider Trading - Loxo Oncology, Inc.

Acțiuni Insider

32.562.197 shares

Scorul de sentimente din interior

Insider Sentiment Score găsește companiile cumpărate de persoane din interior.

Este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de persoane interne. Modelul de scoring folosește o combinație a numărului net de persoane din interior care cumpără în ultimele 90 de zile, totalul acțiunilor cumpărate ca procent din flota și totalul acțiunilor deținute de insider. Numărul variază de la 0 la 100, numerele mai mari indicând un nivel mai ridicat de acumulare pentru semenii săi, iar 50 fiind media.

Frecvența actualizării: zilnic

Vedeți Top Picks Insiders, care oferă o listă a companiilor cu cea mai mare acumulare de persoane din interior.

Vedeți acțiunile cu cea mai înaltă clasare

Scorul de sentiment al ofițerului

Scorul de sentiment al ofițerilor găsește companii cumpărate de ofițerii corporativi.

Prin definiție, Ofițerii Corporativi sunt Corporate Insiders, dar spre deosebire de unii dintre ceilalți Insiders (10% Acționari și Membri ai Consiliului de Administrație), Ofițerii lucrează zilnic pentru companie și își folosesc banii atunci când tranzacționează . (10% acționari și membri ai consiliului de administrație sunt adesea administratori de fonduri care gestionează banii altor persoane.) Ca atare, tranzacțiile privilegiate efectuate de către ofițeri sunt mult mai semnificative și ar trebui tratate în mod corespunzător.

La fel ca Scorul Sentimentului Insider, Scorul Sentimentului Ofițerului este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de ofițeri.

Frecvența actualizării: zilnic

Vedeți Top Picks Insiders, care oferă o listă a companiilor cu cel mai mare sentiment din interior.

Vedeți acțiunile cu cea mai înaltă clasare

Valori cheie ale insiderului

Acest card arată modul în care compania se clasifică de-a lungul diferitelor valori interne. Clasamentul percentilei arată cum se compară această companie cu alte companii de pe piețele din SUA. Clasamentele mai înalte indică situații mai bune.

De exemplu, este în general acceptat că cumpărarea din interior este un indicator pozitiv, astfel încât companiile cu mai multe achiziții din interior s-ar clasa mai sus decât companiile cu mai puține achiziții din interior (sau chiar vânzări din interior).

Numărul net de persoane din interior care cumpără (clasament)

N/A

Numărul net de persoane din interior care cumpără este numărul total de persoane din interior care cumpără minus numărul total de persoane din interior care au vândut în ultimele 90 de zile. Rangul percentilei este afișat aici (interval de la 0 la 100%).

Procent din flota cumpărată de persoane din interior (clasament)

N/A

Procent of Float Bought by Insiders este numărul total de acțiuni cumpărate de insiders minus numărul total de acțiuni vândute de insiders în ultimele 90 de zile, împărțit la flota totală și înmulțit cu 100.

Graficul privind tranzacțiile privilegiate

Loxo Oncology, Inc. tranzacții privilegiate sunt prezentate în graficul următor. Insiders sunt ofițeri, directori sau investitori importanți într-o companie. În general, este în general ilegal ca persoanele din interior să facă tranzacții în companiile lor pe baza unor informații materiale, nepublice. Acest lucru nu înseamnă că este ilegal pentru ei să facă tranzacții în propriile companii. Cu toate acestea, ei trebuie să raporteze toate tranzacțiile către SEC printr-un Formular 4.

Lista de persoane din interior și valori de profitabilitate

Acest tabel prezintă lista persoanelor din interior cunoscute și este generată automat din dosarele dezvăluite SEC. Pe lângă nume, cel mai recent titlu și desemnarea directorului, a ofițerului sau a proprietarului în proporție de 10%, oferim cele mai recente dețineri divulgate. În plus, atunci când este posibil, oferim performanța comercială istorică pentru persoane din interior. Performanța comercială istorică este o medie ponderată a performanței tranzacțiilor reale de cumpărare pe piață deschisă efectuate de către insider. Pentru mai multe informații despre cum se calculează, urmăriți acest webinar YouTube.

See our leaderboard of most profitable insider traders.

Insider	Profit mediu (%)	Acțiuni Deținut	Despică Ajustat

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Înregistrări ale achizițiilor interne - Analiza profitului pe termen scurt

În această secțiune, analizăm profitabilitatea fiecărei achiziții neplanificate, pe piață deschisă, efectuată în LOXO / Loxo Oncology, Inc.. Această analiză ajută la înțelegerea dacă persoana din interior generează în mod constant profituri anormale și merită urmărită. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .

Următorul tabel prezintă cele mai recente achiziții pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.

Data tranzacției	Insider	Raportat Acțiuni	Raportat Preț	Ajustat Acțiuni	Ajustat Preț	Baza costurilor	Zile pentru Max	Pret la Max	Max Profit ($)	Randament maxim (%)
2018-12-13	Naider Avi Z.	725	138,9185	725	138,9185	100.716	54	234.7500	69.479	68,99
2017-01-10	AISLING CAPITAL III LP	160.000	31,0000	160.000	31,0000	4.960.000
2016-05-17	AISLING CAPITAL III LP	232.558	21,5000	232.558	21,5000	4.999.997
2015-12-11	AISLING CAPITAL III LP	200	27,5000	200	27,5000	5.500
2015-11-17	AISLING CAPITAL III LP	265.000	26,5000	265.000	26,5000	7.022.500
2015-11-17	Naider Avi Z.	3.773	26,5000	3.773	26,5000	99.984
2015-11-13	AISLING CAPITAL III LP	1.955	27,4702	1.955	27,4702	53.704
2015-11-12	AISLING CAPITAL III LP	76.714	27,6523	76.714	27,6523	2.121.319
2014-08-06	Naider Avi Z.	3.846	13,0000	3.846	13,0000	49.998

Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.

LOXO / Loxo Oncology, Inc. Insider Trades

Înregistrări ale vânzărilor din interior - Analiza pierderilor pe termen scurt

În această secțiune, analizăm evitarea pierderilor pe termen scurt a fiecărei vânzări neplanificate, pe piață deschisă, efectuată în LOXO / Loxo Oncology, Inc.. Un model consistent de evitare a pierderilor poate sugera că viitoarele tranzacții de vânzare pot prezice scăderi ale prețului. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .

Următorul tabel arată cele mai recente vânzări pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.

Data tranzacției	Insider	Raportat Acțiuni	Raportat Preț	Ajustat Acțiuni	Ajustat Preț	Baza costurilor	Zile pentru Min	Pret la Min	Pierdere maximă Evitat ($)	Pierdere maximă Evitat (%)
2018-07-10	AISLING CAPITAL III LP	1.400.000	179,4300	1.400.000	179,4300	251.202.000	164	127.8000	-72.282.000	-28,77
2018-06-20	Bilenker Joshua H.	9.664	179,7730	9.664	179,7730	1.737.326
2018-06-20	Bilenker Joshua H.	11.336	178,9437	11.336	178,9437	2.028.506
2018-06-19	Bilenker Joshua H.	103	180,3368	103	180,3368	18.575
2018-06-19	Bilenker Joshua H.	3.902	179,8333	3.902	179,8333	701.710
2018-06-19	Bilenker Joshua H.	8.763	178,2970	8.763	178,2970	1.562.417
2018-06-19	Bilenker Joshua H.	8.232	177,4359	8.232	177,4359	1.460.652
2018-06-14	Kunkel Lori Anne	1.541	182,3467	1.541	182,3467	280.996
2018-06-14	Kunkel Lori Anne	2.411	181,4783	2.411	181,4783	437.544

Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.

Istoricul tranzactiilor

Faceți clic pe pictograma link pentru a vedea istoricul complet al tranzacțiilor. Tranzacțiile raportate ca parte a unui plan de tranzacționare automată 10b5-1 vor avea un X în coloana marcată 10b-5.

Fişier Data	Comerț Data	Formă	Insider	Ticker	Titlul de securitate	Cod	Direct	Exercițiu Preț	Unitate Preț	Unități Schimbat	Valoare Schimbat (1K)	Rămas Opțiuni	Rămas Acțiuni
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	139,77	235,0000	-57.000	-13.395	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	84,88	235,0000	-200.000	-47.000	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	43,56	235,0000	-35.000	-8.225	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	26,27	235,0000	-74.000	-17.390	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	31,69	235,0000	-43.000	-10.105	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,67	235,0000	-78.943	-18.552	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-35.026	-8.231	0
2019-02-15	2019-02-15	4	Van Naarden Jacob	LOXO	Common Stock	D - Sale to Issuer	D		235,0000	-19.000	-4.465		0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	139,77	235,0000	-128.000	-30.080	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	84,88	235,0000	-300.000	-70.500	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	43,56	235,0000	-100.000	-23.500	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	26,27	235,0000	-209.000	-49.115	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	31,69	235,0000	-142.000	-33.370	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,67	235,0000	-318.514	-74.851	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-64.471	-15.151	0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	1,18	235,0000	-27.459	-6.453	0
2019-02-15	2019-02-15	4	Bilenker Joshua H. By Joshua H. Bilenker,ttee Joshua Bilenker 2018 GRAT, dated 06/20/2018	LOXO	Common Stock	D - Sale to Issuer	I		235,0000	-30.000	-7.050		0
2019-02-15	2019-02-15	4	Bilenker Joshua H.	LOXO	Common Stock	D - Sale to Issuer	D		235,0000	-162.707	-38.236		0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	139,77	235,0000	-20.000	-4.700	0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	84,88	235,0000	-40.000	-9.400	0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	43,56	235,0000	-12.000	-2.820	0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	31,69	235,0000	-28.000	-6.580	0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	26,27	235,0000	-28.000	-6.580	0
2019-02-15	2019-02-15	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	11,35	235,0000	-17.500	-4.112	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,00	235,0000	-15.625	-3.672	0
2019-02-15	2019-02-15	4	ELMS STEVE	LOXO	Common Stock	U - Other	I		235,0000	-2.038.920	-479.146		2.038.920
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	84,88	235,0000	-2.500	-588	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,67	235,0000	-12.500	-2.938	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,00	235,0000	-15.625	-3.672	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-31.459	-7.393	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	1,18	235,0000	-68.620	-16.126	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	1,18	235,0000	-32.345	-7.601	0
2019-02-15	2019-02-15	4	Flaherty Keith T.	LOXO	Common Stock	D - Sale to Issuer	D		235,0000	-9.732	-2.287		0
2019-02-15	2019-02-15	4	Fuhrman Alan	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	Fuhrman Alan	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	Fuhrman Alan	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Fuhrman Alan	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Fuhrman Alan	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	11,35	235,0000	-13.000	-3.055	0
2019-02-15	2019-02-15	4	Harr Steve	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	Harr Steve	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	Harr Steve	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	19,66	235,0000	-15.625	-3.672	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-3.095	-727	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-4.716	-1.108	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-49.687	-11.676	0
2019-02-15	2019-02-15	4	Kunkel Lori Anne	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-27.344	-6.426	0
2019-02-15	2019-02-15	4	MAYLEBEN TIMOTHY M	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	MAYLEBEN TIMOTHY M	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	MAYLEBEN TIMOTHY M	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-5.228	-1.229	0
2019-02-15	2019-02-15	4	MAYLEBEN TIMOTHY M	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-5.209	-1.224	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	180,98	235,0000	-8.750	-2.056	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	78,58	235,0000	-11.000	-2.585	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	20,91	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	24,18	235,0000	-7.812	-1.836	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,00	235,0000	-15.625	-3.672	0
2019-02-15	2019-02-15	4	Naider Avi Z.	LOXO	Common Stock	D - Sale to Issuer	D		235,0000	-111.843	-26.283		0
2019-02-15	2019-01-31	4	Naider Avi Z.	LOXO	Common Stock	G - Gift	D			-15.000			111.843
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	139,77	235,0000	-37.000	-8.695	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	84,88	235,0000	-75.000	-17.625	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	43,56	235,0000	-12.000	-2.820	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	26,27	235,0000	-18.375	-4.318	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	27,00	235,0000	-14.870	-3.494	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	31,69	235,0000	-9.228	-2.169	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	13,67	235,0000	-10.861	-2.552	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	3,65	235,0000	-4.557	-1.071	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	1,18	235,0000	-14.828	-3.485	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	D - Sale to Issuer	D	1,18	235,0000	-16.983	-3.991	0
2019-02-15	2019-02-15	4	Nanda Nisha	LOXO	Common Stock	D - Sale to Issuer	D		235,0000	-18.896	-4.441		0
2019-01-17	2018-07-09	4/A	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		141.207
2019-01-17	2018-07-09	4/A	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		13.541
2019-01-02	2019-01-02	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	A - Award	D	139,77		128.000		128.000
2019-01-02	2019-01-02	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	A - Award	D	139,77		57.000		57.000
2019-01-02	2019-01-02	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	A - Award	D	139,77		20.000		20.000
2019-01-02	2019-01-02	4	Nanda Nisha	LOXO	Employee Stock Option (Right to Buy)	A - Award	D	139,77		37.000		37.000
2019-01-02		3	Nanda Nisha	LOXO	Common Stock		D						37.792
2019-01-02		3	Nanda Nisha	LOXO	Common Stock		D						37.792
2019-01-02		3	Nanda Nisha	LOXO	Common Stock		D						37.792
2018-12-17	2018-12-13	4	Naider Avi Z.	LOXO	Common Stock	P - Purchase	D		138,9185	725	101		126.843
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-7.000		33.326
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-4.500		78.943
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	7.000	26		20.700
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		140,1600	-541	-76		13.700
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		139,2300	-500	-70		14.241
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		137,7300	-500	-69		14.741
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		137,0900	-1.759	-241		15.241
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		135,9200	-800	-109		17.000
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		134,7400	-400	-54		17.800
2018-12-12	2018-12-11	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		13,6700	4.500	62		18.200
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-4.500		83.443
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		137,3900	-100	-14		13.700
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		136,4800	-200	-27		13.800
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		135,1400	-500	-68		14.000
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		134,6500	-1.400	-189		14.500
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		133,1700	-900	-120		15.900
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		132,2300	-1.000	-132		16.800
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		130,5900	-400	-52		17.800
2018-12-12	2018-12-10	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		13,6700	4.500	62		18.200
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-10.000		318.514
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		140,6100	-100	-14		164.407
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		140,1500	-1.200	-168		164.507
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		139,0500	-1.100	-153		165.707
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		137,6300	-2.407	-331		166.807
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		136,7900	-3.393	-464		169.214
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		135,7600	-1.153	-157		172.607
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		134,6300	-647	-87		173.760
2018-12-12	2018-12-11	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		13,6700	10.000	137		174.407
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-10.000		328.514
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		137,3900	-100	-14		164.407
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		136,4800	-400	-55		164.507
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		135,0400	-2.377	-321		164.907
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		134,3100	-2.049	-275		167.284
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		133,0000	-2.104	-280		169.333
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,0900	-2.001	-264		171.437
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		130,5800	-969	-127		173.438
2018-12-12	2018-12-10	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		13,6700	10.000	137		174.407
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		17.500
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		140,4800	-100	-14		0
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		139,3600	-100	-14		100
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		137,8800	-263	-36		200
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		136,9800	-587	-80		463
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		135,6900	-200	-27		1.050
2018-12-12	2018-12-11	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		18.750
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		136,0400	-100	-14		0
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		134,7100	-550	-74		100
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		133,3400	-100	-13		650
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		132,4400	-400	-53		750
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		130,7900	-100	-13		1.150
2018-12-12	2018-12-10	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-10.000		338.514
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		151,5600	-200	-30		164.407
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		149,2500	-400	-60		164.607
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		148,0600	-250	-37		165.007
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		147,0900	-600	-88		165.257
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		144,6100	-700	-101		165.857
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		143,3500	-859	-123		166.557
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		142,4500	-634	-90		167.416
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		141,4800	-690	-98		168.050
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		140,1400	-700	-98		168.740
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		138,9400	-2.638	-367		169.440
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		137,9200	-2.329	-321		172.078
2018-11-28	2018-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		13,6700	10.000	137		174.407
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-1.486		348.514
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,68		-8.514		64.471
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	1,18		-29.000		27.459
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		156,2000	-664	-104		164.407
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		155,0800	-2.210	-343		165.071
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		154,0700	-676	-104		167.281
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		152,7500	-1.995	-305		167.957
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		152,0400	-3.655	-556		169.952
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		150,9900	-800	-121		173.607
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		13,6700	1.486	20		174.407
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		3,6480	8.514	31		172.921
2018-11-28	2018-11-26	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	29.000	34		164.407
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		20.000
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		151,5500	-100	-15		0
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		148,2000	-100	-15		100
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		147,0900	-100	-15		200
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		143,8400	-200	-29		300
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		140,9400	-200	-28		500
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		138,9500	-350	-49		700
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		137,8900	-200	-28		1.050
2018-11-28	2018-11-27	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		21.250
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		156,0400	-100	-16		0
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		155,1300	-300	-47		100
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		153,3000	-100	-15		400
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		152,3900	-250	-38		500
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		151,5700	-500	-76		750
2018-11-28	2018-11-26	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	13,67		-2.057		87.943
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-2.443		40.326
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		151,5500	-200	-30		13.700
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		149,4600	-200	-30		13.900
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		147,9900	-81	-12		14.100
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		147,0600	-300	-44		14.181
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		144,9700	-100	-14		14.481
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		143,9200	-200	-29		14.581
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		143,0800	-500	-72		14.781
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		141,6900	-500	-71		15.281
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		140,1300	-300	-42		15.781
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		138,8300	-1.170	-162		16.081
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		138,0800	-949	-131		17.251
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		13,6700	2.057	28		18.200
2018-11-28	2018-11-27	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	2.443	9		16.143
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-5.500		42.769
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		156,4500	-200	-31		13.700
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		155,3000	-600	-93		13.900
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		154,0000	-1.500	-231		14.500
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		152,4900	-1.644	-251		16.000
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		151,7100	-1.556	-236		17.644
2018-11-28	2018-11-26	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	5.500	20		19.200
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-10.000		72.985
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		165,5689	-200	-33		135.407
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		164,5921	-1.395	-230		135.607
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		163,6428	-2.000	-327		137.002
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		162,6041	-3.152	-513		139.002
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		161,4096	-1.553	-251		142.154
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		160,6138	-1.700	-273		143.707
2018-10-05	2018-10-04	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		3,6480	10.000	36		145.407
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-10.000		82.985
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		169,6779	-195	-33		135.407
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		169,0030	-3.705	-626		135.602
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		168,2902	-1.297	-218		139.307
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		167,0908	-673	-112		140.604
2018-10-05	2018-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		165,9477	-1.225	-203		141.277
2018-10-05	2001-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		165,0058	-2.905	-479		142.502
2018-10-05	2001-10-03	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		3,6480	10.000	36		145.407
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		22.500
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		165,0500	-200	-33		0
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		164,2500	-200	-33		200
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		162,5366	-311	-51		400
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		161,2155	-539	-87		711
2018-10-05	2018-10-04	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-10-05	2018-10-03	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		23.750
2018-10-05	2018-10-03	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		168,9723	-560	-95		0
2018-10-05	2018-10-03	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		167,1000	-100	-17		560
2018-10-05	2018-10-03	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		165,5278	-590	-98		660
2018-10-05	2018-10-03	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		164,6767	-600	-99		13.700
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		163,7845	-1.006	-165		14.300
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		162,7010	-1.194	-194		15.306
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		161,5205	-1.100	-178		16.500
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		160,6217	-600	-96		17.600
2018-10-05	2018-10-04	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	4.500	16		18.200
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-5.500		52.769
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		169,4000	-300	-51		13.700
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		168,8465	-2.300	-388		14.000
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		167,1920	-500	-84		16.300
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		165,8850	-400	-66		16.800
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		165,1303	-2.000	-330		17.200
2018-10-05	2018-10-03	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	5.500	20		19.200
2018-10-05	2001-10-04	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-4.500		48.269
2018-10-03	2018-10-01	4	Kunkel Lori Anne	LOXO	Director Stock Option (Right to Buy)	M - Exercise	D	3,65		-5.000		22.344
2018-10-03	2018-10-01	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		171,8960	-500	-86		0
2018-10-03	2018-10-01	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		170,1958	-4.500	-766		500
2018-10-03	2018-10-01	4	Kunkel Lori Anne	LOXO	Common Stock	M - Exercise	D		3,6480	5.000	18		5.000
2018-09-14	2018-09-13	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-4.500		58.269
2018-09-14	2018-09-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		167,4867	-300	-50		13.700
2018-09-14	2018-09-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		166,6347	-1.500	-250		14.000
2018-09-14	2018-09-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		165,4463	-2.700	-447		15.500
2018-09-14	2018-09-13	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	4.500	16		18.200
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-5.500		62.769
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		171,0267	-600	-103		13.700
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		168,7850	-200	-34		14.300
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		167,3920	-1.000	-167		14.500
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		166,7380	-1.059	-177		15.500
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		165,3156	-1.885	-312		16.559
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		164,4383	-756	-124		18.444
2018-09-14	2018-09-12	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	5.500	20		19.200
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-2.527		92.985
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	1,18		-7.473		56.459
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		167,3169	-962	-161		135.407
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		166,5230	-3.402	-567		136.369
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		165,4250	-5.636	-932		139.771
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		3,6480	2.527	9		145.407
2018-09-14	2018-09-13	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.473	9		142.880
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	1,18		-10.000		63.932
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		171,0750	-400	-68		135.407
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		169,8872	-200	-34		135.807
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		168,5125	-800	-135		136.007
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		167,3814	-1.800	-301		136.807
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		166,4875	-2.400	-400		138.607
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		165,1821	-3.700	-611		141.007
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		164,1594	-700	-115		144.707
2018-09-14	2018-09-12	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	10.000	12		145.407
2018-09-14	2018-09-13	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		25.000
2018-09-14	2018-09-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		166,7560	-500	-83		0
2018-09-14	2018-09-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		165,5267	-750	-124		500
2018-09-14	2018-09-13	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		26.250
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		170,9500	-300	-51		0
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		168,7850	-200	-34		300
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		167,2500	-200	-33		500
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		166,1391	-550	-91		700
2018-09-14	2018-09-12	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-08-15	2018-08-14	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	1,18		-10.000		73.932
2018-08-15	2018-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		160,7508	-1.300	-209		135.407
2018-08-15	2018-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		159,9311	-7.100	-1.136		136.707
2018-08-15	2018-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		159,1263	-1.600	-255		143.807
2018-08-15	2018-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	10.000	12		145.407
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	1,18		-10.000		83.932
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		160,4862	-800	-128		135.407
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		159,6267	-3.367	-537		136.207
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		158,5098	-4.233	-671		139.574
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		157,6677	-1.600	-252		143.807
2018-08-15	2018-08-13	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	10.000	12		145.407
2018-08-15	2018-08-14	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		27.500
2018-08-15	2018-08-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		160,6488	-800	-129		0
2018-08-15	2018-08-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		159,4656	-450	-72		800
2018-08-15	2018-08-14	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-08-15	2018-08-13	4	Burstein Jennifer	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	11,35		-1.250		28.750
2018-08-15	2018-08-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		160,1700	-10	-2		0
2018-08-15	2018-08-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		158,6882	-440	-70		10
2018-08-15	2018-08-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		158,0025	-800	-126		450
2018-08-15	2018-08-13	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.250	14		1.250
2018-08-15	2018-08-14	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-4.500		68.269
2018-08-15	2018-08-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		160,6997	-701	-113		13.700
2018-08-15	2018-08-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		159,9070	-3.199	-512		14.401
2018-08-15	2018-08-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		159,0820	-600	-95		17.600
2018-08-15	2018-08-14	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	4.500	16		18.200
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Employee Stock Option (Right to Buy)	M - Exercise	D	3,65		-5.500		72.769
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		160,5950	-200	-32		13.700
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		159,6893	-1.500	-240		13.900
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		158,6619	-3.070	-487		15.400
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		157,6155	-730	-115		18.470
2018-08-15	2018-08-13	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	5.500	20		19.200
2018-07-12	2018-07-10	4	AISLING CAPITAL III LP	LOXO	Common Stock	S - Sale	D		179,4300	-1.400.000	-251.202		2.038.920
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		93.932
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		182,8388	-800	-146		135.407
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		181,2077	-1.300	-236		136.207
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		180,0810	-1.000	-180		137.507
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		179,0809	-2.200	-394		138.507
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		178,1923	-2.200	-392		140.707
2018-07-11	2018-07-10	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		142.907
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		101.432
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		191,6333	-300	-57		135.407
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		189,4300	-300	-57		135.707
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		188,2849	-802	-151		136.007
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		187,3871	-3.698	-693		136.809
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		186,3849	-1.500	-280		140.507
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		184,8698	-900	-166		142.007
2018-07-11	2018-07-09	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		142.907
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		78.269
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		183,1900	-100	-18		13.700
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		181,9600	-100	-18		13.800
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		180,9467	-300	-54		13.900
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		179,5006	-361	-65		14.200
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		178,3943	-680	-121		14.561
2018-07-11	2018-07-10	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		15.241
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		79.810
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		191,6400	-100	-19		13.700
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		189,1200	-100	-19		13.800
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		188,0400	-200	-38		13.900
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		187,3749	-641	-120		14.100
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		186,1900	-200	-37		14.741
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		185,3402	-300	-56		14.941
2018-07-11	2018-07-09	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		15.241
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.500		30.000
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		191,6400	-100	-19		0
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		189,1200	-100	-19		100
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		187,5283	-600	-113		200
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		186,6660	-500	-93		800
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		184,7200	-200	-37		1.300
2018-07-11	2018-07-09	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.500	17		1.500
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		108.932
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-28.000		116.432
2018-06-21	2018-06-20	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		179,7730	-9.664	-1.737		8.000
2018-06-21	2018-06-20	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		178,9437	-11.336	-2.029		17.664
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		180,8965	-430	-78		155.707
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		179,3697	-4.370	-784		156.137
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		178,8052	-2.700	-483		160.507
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		163.207
2018-06-21	2018-06-20	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	28.000	33		155.707
2018-06-21	2018-06-19	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		144.432
2018-06-21	2018-06-19	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		180,3368	-103	-19		29.000
2018-06-21	2018-06-19	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		179,8333	-3.902	-702		29.103
2018-06-21	2018-06-19	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		178,2970	-8.763	-1.562		33.005
2018-06-21	2018-06-19	4	Bilenker Joshua H. By Joshua H. Bilenker, Trustee for the Joshua H. Bilenker 2017 GRAT u/a DTD 06/16/17	LOXO	Common Stock	S - Sale	I		177,4359	-8.232	-1.461		41.768
2018-06-21	2018-06-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		178,1172	-1.737	-309		127.707
2018-06-21	2018-06-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		177,0556	-3.427	-607		129.444
2018-06-21	2018-06-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		176,2016	-2.336	-412		132.871
2018-06-21	2018-06-19	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		135.207
2018-06-21	2018-06-08	4	Bilenker Joshua H.	LOXO	Common Stock	G - Gift	D			-5.000			127.707
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		83.051
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-12.000		84.592
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		180,9000	-200	-36		12.000
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		179,7550	-200	-36		12.200
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		179,0001	-1.141	-204		12.400
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		13.541
2018-06-21	2018-06-20	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	12.000	44		12.000
2018-06-21	2018-06-19	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		96.592
2018-06-21	2018-06-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		178,2300	-100	-18		0
2018-06-21	2018-06-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		177,4674	-576	-102		100
2018-06-21	2018-06-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		176,4413	-865	-153		676
2018-06-21	2018-06-19	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-06-21	2018-06-19	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		31.500
2018-06-21	2018-06-19	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		178,2025	-400	-71		0
2018-06-21	2018-06-19	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		177,1500	-500	-89		400
2018-06-21	2018-06-19	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		176,2898	-800	-141		900
2018-06-21	2018-06-19	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2018-06-18	2018-06-15	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		177,7900	-4	-1		0
2018-06-18	2018-06-15	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		177,1217	-5.601	-992		4
2018-06-18	2018-06-15	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		175,6434	-1.235	-217		5.605
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	M - Exercise	D	24,18		-1.953		5.859
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	M - Exercise	D	20,91		-3.096		4.716
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	M - Exercise	D	3,65		-27.343		27.344
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		182,3467	-1.541	-281		6.840
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		181,4783	-2.411	-438		8.381
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		180,2751	-28.440	-5.127		10.792
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	M - Exercise	D		24,1800	1.953	47		39.232
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	M - Exercise	D		20,9100	3.096	65		37.279
2018-06-18	2018-06-14	4	Kunkel Lori Anne	LOXO	Common Stock	M - Exercise	D		3,6480	27.343	100		34.183
2018-06-14	2018-06-13	4	Naider Avi Z.	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	ELMS STEVE	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	Harr Steve	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-14	2018-06-13	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	A - Award	D	180,98		8.750		8.750
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	M - Exercise	D	1,18		-50.000		32.345
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		175,9712	-5.422	-954		9.732
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		175,1004	-4.743	-831		15.154
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		174,0446	-16.037	-2.791		19.897
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		173,3220	-12.243	-2.122		35.934
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		172,0348	-4.634	-797		48.177
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		171,1530	-5.021	-859		52.811
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		169,8458	-1.900	-323		57.832
2018-06-11	2018-06-07	4	Flaherty Keith T.	LOXO	Common Stock	M - Exercise	D		1,1840	50.000	59		59.732
2018-06-11	2018-06-08	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	M - Exercise	D	11,35		-2.625		13.000
2018-06-11	2018-06-08	4	Fuhrman Alan	LOXO	Common Stock	S - Sale	D		178,0711	-2.625	-467		0
2018-06-11	2018-06-08	4	Fuhrman Alan	LOXO	Common Stock	M - Exercise	D		11,3500	2.625	30		2.625
2018-06-11	2018-06-08	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	M - Exercise	D	24,18		-2.584		5.228
2018-06-11	2018-06-08	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	M - Exercise	D	20,91		-7.416		5.209
2018-06-11	2018-06-08	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	S - Sale	D		179,5469	-10.000	-1.795		0
2018-06-11	2018-06-08	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	M - Exercise	D		24,1800	2.584	62		10.000
2018-06-11	2018-06-08	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	M - Exercise	D		20,9100	7.416	155		7.416
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		14.690
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		138,8883	-1.803	-250		182.707
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		138,3521	-3.297	-456		184.510
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		136,7200	-400	-55		187.807
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		135,8280	-1.000	-136		188.207
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		134,4067	-300	-40		189.207
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		133,1065	-700	-93		189.507
2018-05-16	2018-05-15	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		22.190
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		139,0017	-100	-14		182.707
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		137,8319	-167	-23		182.807
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		137,2763	-1.558	-214		182.974
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		136,2166	-1.525	-208		184.532
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		135,0827	-2.050	-277		186.057
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		134,1845	-2.000	-268		188.107
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,5800	-100	-13		190.107
2018-05-16	2018-05-14	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		33.200
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		139,0865	-290	-40		0
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		138,1881	-210	-29		290
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		137,3289	-700	-96		500
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		135,0933	-300	-41		1.200
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		133,8550	-200	-27		1.500
2018-05-16	2018-05-14	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		98.133
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		139,0400	-200	-28		0
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		138,3518	-841	-116		200
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		135,7800	-300	-41		1.041
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		133,3500	-200	-27		1.341
2018-05-16	2018-05-15	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		99.674
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		139,4500	-9	-1		0
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		138,7007	-691	-96		9
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		137,4958	-600	-82		700
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		134,2496	-241	-32		1.300
2018-05-16	2018-05-14	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		29.690
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,5300	-100	-13		182.707
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		131,8418	-3.400	-448		182.807
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		130,7121	-2.400	-314		186.207
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		129,4438	-800	-104		188.607
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		128,3045	-800	-103		189.407
2018-04-26	2018-04-25	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		37.190
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		133,4851	-510	-68		182.707
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,5426	-2.490	-330		183.217
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		131,7567	-1.500	-198		185.707
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		130,6232	-1.283	-168		187.207
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		129,3516	-1.717	-222		188.490
2018-04-26	2018-04-24	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		101.215
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		132,0546	-541	-71		0
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		130,9350	-600	-79		541
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		129,4500	-100	-13		1.141
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		128,7167	-300	-39		1.241
2018-04-26	2018-04-25	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		102.756
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		133,0860	-500	-67		0
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		131,8820	-500	-66		500
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		130,6167	-300	-39		1.000
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		129,5810	-241	-31		1.300
2018-04-26	2018-04-24	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		34.900
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		133,6233	-300	-40		0
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		132,0625	-800	-106		300
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		130,7700	-300	-39		1.100
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		129,4551	-300	-39		1.400
2018-04-26	2018-04-24	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2018-04-24	2018-04-20	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		133,6000	-100	-13		6.840
2018-04-24	2018-04-20	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		132,8097	-4.000	-531		6.940
2018-04-24	2018-04-20	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		131,9772	-900	-119		10.940
2018-03-15	2018-03-14	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		44.690
2018-03-15	2018-03-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,2550	-1.400	-185		182.707
2018-03-15	2018-03-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		131,5983	-4.300	-566		184.107
2018-03-15	2018-03-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		130,6584	-1.800	-235		188.407
2018-03-15	2018-03-14	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		52.190
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		133,5044	-1.491	-199		182.707
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		132,5781	-1.094	-145		184.198
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		131,7597	-1.715	-226		185.292
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		130,6906	-1.800	-235		187.007
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		129,9665	-1.100	-143		188.807
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		128,5733	-300	-39		189.907
2018-03-15	2018-03-13	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-03-15	2018-03-14	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		104.297
2018-03-15	2018-03-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		132,0227	-646	-85		0
2018-03-15	2018-03-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		131,0540	-895	-117		646
2018-03-15	2018-03-14	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		105.838
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		134,0500	-100	-13		0
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		132,4784	-441	-58		100
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		131,4050	-400	-53		541
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		130,2800	-500	-65		941
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		128,8500	-100	-13		1.441
2018-03-15	2018-03-13	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		36.600
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		134,2800	-100	-13		0
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		133,0400	-300	-40		100
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		131,7540	-500	-66		400
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		130,2286	-700	-91		900
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		128,8500	-100	-13		1.600
2018-03-15	2018-03-13	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		38.300
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		94,7300	-100	-9		0
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		94,0401	-700	-66		100
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		92,8650	-600	-56		800
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		91,6133	-300	-27		1.400
2018-02-14	2018-02-12	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		107.379
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		101,0455	-1.041	-105		0
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		97,8700	-100	-10		1.041
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		96,6000	-100	-10		1.141
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		94,3300	-300	-28		1.241
2018-02-14	2018-02-13	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-02-14	2018-02-12	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		108.920
2018-02-14	2018-02-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		94,4933	-300	-28		0
2018-02-14	2018-02-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		93,8254	-741	-70		300
2018-02-14	2018-02-12	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		92,2100	-500	-46		1.041
2018-02-14	2018-02-12	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		59.690
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		102,2029	-700	-72		182.707
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		101,1888	-3.996	-404		183.407
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		100,3344	-791	-79		187.403
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		98,6225	-400	-39		188.194
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		97,1400	-100	-10		188.594
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		96,4718	-413	-40		188.694
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		94,4445	-1.100	-104		189.107
2018-02-14	2018-02-13	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		67.190
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		94,6842	-1.101	-104		182.707
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		93,7701	-3.942	-370		183.808
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		92,6139	-1.207	-112		187.750
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		91,7623	-1.250	-115		188.957
2018-02-14	2018-02-12	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-01-25	2018-01-22	4	Naider Avi Z.	LOXO	Common Stock	S - Sale	D		100,0000	-15.000	-1.500		126.118
2018-01-25	2018-01-22	4	Naider Avi Z.	LOXO	Common Stock	G - Gift	D			-3.000			141.118
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		74.690
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,5249	-2.682	-240		182.707
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		88,8921	-2.672	-238		185.389
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,1416	-1.042	-91		188.061
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		86,1929	-1.104	-95		189.103
2018-01-18	2018-01-17	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		82.190
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		90,4964	-800	-72		182.707
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,9387	-1.577	-142		183.507
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		88,7767	-600	-53		185.084
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,1245	-1.604	-140		185.684
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		86,4236	-2.919	-252		187.288
2018-01-18	2018-01-16	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		110.461
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,8650	-200	-18		0
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,2259	-695	-62		200
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		87,9600	-200	-18		895
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		86,2953	-446	-38		1.095
2018-01-18	2018-01-17	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		112.002
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		90,4500	-100	-9		0
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		90,0700	-500	-45		100
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		88,3600	-100	-9		600
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		87,0950	-200	-17		700
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		86,5316	-641	-55		900
2018-01-18	2018-01-16	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2018-01-18	2018-01-16	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.500		40.000
2018-01-18	2018-01-16	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		87,4952	-1.500	-131		0
2018-01-18	2018-01-16	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.500	17		1.500
2018-01-05	2018-01-04	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	A - Award	D	84,88		300.000		300.000
2018-01-05	2018-01-04	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	A - Award	D	84,88		200.000		200.000
2018-01-05	2018-01-04	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	A - Award	D	84,88		40.000		40.000
2018-01-05	2018-01-04	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	84,88		2.500		2.500
2017-12-22	2017-12-20	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	S - Sale	D		80,4948	-10.000	-805		0
2017-12-20	2017-12-19	4	AISLING CAPITAL III LP	LOXO	Common Stock	S - Sale	D		80,5000	-250.000	-20.125		3.438.920
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		113.543
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		82,8600	-100	-8		0
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		80,7900	-200	-16		100
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		79,6906	-241	-19		300
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		78,7183	-600	-47		541
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		77,6025	-400	-31		1.141
2017-12-18	2017-12-15	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-12-18	2017-12-14	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		115.084
2017-12-18	2017-12-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		84,0114	-700	-59		0
2017-12-18	2017-12-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		82,6527	-841	-70		700
2017-12-18	2017-12-14	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-12-18	2017-12-14	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		41.500
2017-12-18	2017-12-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		83,9447	-800	-67		0
2017-12-18	2017-12-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		82,6646	-900	-74		800
2017-12-18	2017-12-14	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		89.690
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		82,8600	-200	-17		182.707
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		81,7200	-100	-8		182.907
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		80,8817	-600	-49		183.007
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		80,0822	-609	-49		183.607
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		78,9932	-3.023	-239		184.216
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		78,0645	-2.268	-177		187.239
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		76,9271	-700	-54		189.507
2017-12-18	2017-12-15	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2017-12-18	2017-12-14	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		97.190
2017-12-18	2017-12-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		84,2935	-2.000	-169		182.707
2017-12-18	2017-12-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		83,4179	-2.900	-242		184.707
2017-12-18	2017-12-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		82,5465	-2.600	-215		187.607
2017-12-18	2017-12-14	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2017-12-12	2017-12-08	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		82,5000	-250.000	-20.625		941.000
2017-12-12	2017-12-08	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		82,5000	-250.000	-20.625		941.000
2017-11-29	2017-11-28	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		116.625
2017-11-29	2017-11-28	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		75,5187	-441	-33		0
2017-11-29	2017-11-28	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		74,0340	-500	-37		441
2017-11-29	2017-11-28	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		73,2683	-600	-44		941
2017-11-29	2017-11-28	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-11-29	2017-11-27	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		118.166
2017-11-29	2017-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		76,7633	-300	-23		0
2017-11-29	2017-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		74,9625	-400	-30		300
2017-11-29	2017-11-27	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		74,0811	-841	-62		700
2017-11-29	2017-11-27	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-11-29	2017-11-27	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		43.200
2017-11-29	2017-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		76,7633	-300	-23		0
2017-11-29	2017-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		75,1833	-300	-23		300
2017-11-29	2017-11-27	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		74,1900	-1.100	-82		600
2017-11-29	2017-11-27	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		104.690
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		75,8524	-790	-60		182.707
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		75,2095	-1.850	-139		183.497
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		73,9936	-2.460	-182		185.347
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		73,1513	-2.400	-176		187.807
2017-11-29	2017-11-28	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		112.190
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		77,0733	-300	-23		182.707
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		76,1989	-906	-69		183.007
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		74,9838	-1.601	-120		183.913
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		74,1302	-4.693	-348		185.514
2017-11-29	2017-11-27	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		190.207
2017-11-29	2017-11-20	4	Bilenker Joshua H.	LOXO	Common Stock	G - Gift	D			-6.000			182.707
2017-11-27	2017-11-22	4	AISLING CAPITAL III LP	LOXO	Common Stock	S - Sale	D		75,0000	-500.000	-37.500		3.688.920
2017-11-27	2017-11-22	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	M - Exercise	D	20,91		-3.000		12.625
2017-11-27	2017-11-22	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	S - Sale	D		75,8542	-3.000	-228		10.000
2017-11-27	2017-11-22	4	MAYLEBEN TIMOTHY M	LOXO	Common Stock	M - Exercise	D		20,9100	3.000	63		13.000
2017-11-27	2017-11-22	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		75,0000	-267.000	-20.025		1.191.000
2017-11-27	2017-11-22	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		75,0000	-267.000	-20.025		1.191.000
2017-11-22	2017-11-20	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		77,3321	-1.961	-152		9.732
2017-11-22	2017-11-20	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		76,2900	-800	-61		11.693
2017-11-22	2017-11-20	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		75,3489	-4.489	-338		12.493
2017-11-20	2017-11-16	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		76,2300	-8.377	-639		1.458.000
2017-11-20	2017-11-16	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		75,3700	-71.598	-5.396		1.466.377
2017-11-20	2017-11-16	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		74,4900	-100.045	-7.452		1.537.975
2017-11-20	2017-11-16	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		73,4800	-43.300	-3.182		1.638.020
2017-11-20	2017-11-16	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		72,4600	-46.680	-3.382		1.681.320
2017-11-20	2017-11-16	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		76,2300	-8.377	-639		1.458.000
2017-11-20	2017-11-16	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		75,3700	-71.598	-5.396		1.466.377
2017-11-20	2017-11-16	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		74,4900	-100.045	-7.452		1.537.975
2017-11-20	2017-11-16	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		73,4800	-43.300	-3.182		1.638.020
2017-11-20	2017-11-16	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		72,4600	-46.680	-3.382		1.681.320
2017-11-06	2017-11-02	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		86,2775	-400	-35		11.840
2017-11-06	2017-11-02	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		85,2109	-2.800	-239		12.240
2017-11-06	2017-11-02	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		84,1494	-1.800	-151		15.040
2017-11-01	2017-10-31	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		119.690
2017-11-01	2017-10-31	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,6650	-200	-18		188.707
2017-11-01	2017-10-31	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		86,6545	-4.339	-376		188.907
2017-11-01	2017-10-31	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		86,1788	-2.961	-255		193.246
2017-11-01	2017-10-31	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-11-01	2017-10-30	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		127.190
2017-11-01	2017-10-30	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		88,7737	-812	-72		188.707
2017-11-01	2017-10-30	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,7386	-998	-88		189.519
2017-11-01	2017-10-30	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		86,8752	-5.690	-494		190.517
2017-11-01	2017-10-30	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-11-01	2017-10-31	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		119.707
2017-11-01	2017-10-31	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		86,9450	-400	-35		0
2017-11-01	2017-10-31	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		86,3655	-1.141	-99		400
2017-11-01	2017-10-31	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-11-01	2017-10-30	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		121.248
2017-11-01	2017-10-30	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		88,7700	-200	-18		0
2017-11-01	2017-10-30	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		87,7796	-241	-21		200
2017-11-01	2017-10-30	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		86,8718	-1.100	-96		441
2017-11-01	2017-10-30	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-11-01	2017-10-30	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		44.900
2017-11-01	2017-10-30	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		88,5500	-200	-18		0
2017-11-01	2017-10-30	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		87,7735	-200	-18		200
2017-11-01	2017-10-30	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		86,8877	-1.300	-113		400
2017-11-01	2017-10-30	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2017-10-18	2017-10-16	4	Naider Avi Z.	LOXO	Common Stock	S - Sale	D		90,0000	-5.000	-450		144.118
2017-09-20	2017-09-18	4	Naider Avi Z.	LOXO	Common Stock	S - Sale	D		90,0000	-5.000	-450		149.118
2017-09-20	2017-09-18	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		46.600
2017-09-20	2017-09-18	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		90,1100	-100	-9		0
2017-09-20	2017-09-18	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		89,4985	-957	-86		100
2017-09-20	2017-09-18	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		88,3494	-643	-57		1.057
2017-09-20	2017-09-18	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2017-09-20	2017-09-19	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		134.690
2017-09-20	2017-09-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,4764	-2.263	-202		188.707
2017-09-20	2017-09-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,0292	-2.873	-256		190.970
2017-09-20	2017-09-19	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,8188	-2.364	-208		193.843
2017-09-20	2017-09-19	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		142.190
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		90,5550	-200	-18		188.707
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,8754	-2.817	-253		188.907
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		89,0921	-3.379	-301		191.724
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		87,9294	-1.104	-97		195.103
2017-09-20	2017-09-18	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-09-20	2017-09-19	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		122.789
2017-09-20	2017-09-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,7600	-100	-9		0
2017-09-20	2017-09-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,1785	-944	-84		100
2017-09-20	2017-09-19	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		87,8609	-497	-44		1.044
2017-09-20	2017-09-19	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-09-20	2017-09-18	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		124.330
2017-09-20	2017-09-18	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,9919	-485	-44		0
2017-09-20	2017-09-18	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		89,1971	-700	-62		485
2017-09-20	2017-09-18	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		88,1396	-356	-31		1.185
2017-09-20	2017-09-18	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-09-15	2017-09-13	4	Naider Avi Z.	LOXO	Common Stock	S - Sale	D		90,0000	-5.000	-450		154.118
2017-08-23	2017-08-21	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		72,6460	-3.450	-251		16.982
2017-08-23	2017-08-21	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		71,9091	-3.800	-273		20.432
2017-08-23	2017-08-22	4	Kunkel Lori Anne	LOXO	Common Stock	S - Sale	D		75,1731	-10.000	-752		16.840
2017-08-16	2017-08-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		149.690
2017-08-16	2017-08-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		73,8346	-936	-69		188.707
2017-08-16	2017-08-15	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		73,3293	-6.564	-481		189.643
2017-08-16	2017-08-15	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-08-16	2017-08-14	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	1,18		-7.500		157.190
2017-08-16	2017-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		74,1226	-2.483	-184		188.707
2017-08-16	2017-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	S - Sale	D		73,5418	-5.017	-369		191.190
2017-08-16	2017-08-14	4	Bilenker Joshua H.	LOXO	Common Stock	M - Exercise	D		1,1840	7.500	9		196.207
2017-08-16	2017-08-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		125.871
2017-08-16	2017-08-15	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		73,4158	-1.541	-113		0
2017-08-16	2017-08-15	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-08-16	2017-08-14	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-1.541		127.412
2017-08-16	2017-08-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		74,0740	-541	-40		0
2017-08-16	2017-08-14	4	Van Naarden Jacob	LOXO	Common Stock	S - Sale	D		73,5450	-1.000	-74		541
2017-08-16	2017-08-14	4	Van Naarden Jacob	LOXO	Common Stock	M - Exercise	D		3,6480	1.541	6		1.541
2017-08-16	2017-08-14	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	11,35		-1.700		48.300
2017-08-16	2017-08-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		74,1667	-600	-45		0
2017-08-16	2017-08-14	4	Burstein Jennifer	LOXO	Common Stock	S - Sale	D		73,4973	-1.100	-81		600
2017-08-16	2017-08-14	4	Burstein Jennifer	LOXO	Common Stock	M - Exercise	D		11,3500	1.700	19		1.700
2017-06-23	2017-06-22	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	Harr Steve	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	Naider Avi Z.	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	Bonita David P	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	ELMS STEVE	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-06-23	2017-06-22	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	78,58		11.000		11.000
2017-05-24	2017-05-22	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		46,2364	-110	-5		24.232
2017-05-24	2017-05-22	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		45,7481	-2.799	-128		24.342
2017-05-24	2017-05-22	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		44,6444	-4.341	-194		27.141
2017-03-17	2017-03-15	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	A - Award	D	43,56		100.000		100.000
2017-03-17	2017-03-15	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	A - Award	D	43,56		35.000		35.000
2017-03-17	2017-03-15	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	A - Award	D	43,56		12.000		12.000
2017-02-23	2017-02-21	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		41,4506	-7.250	-301		31.482
2017-01-12	2017-01-10	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		31,0000	160.000	4.960		4.188.920
2016-12-21	2016-12-19	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		30,2300	-7.250	-219		38.732
2016-12-08	2016-12-06	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	A - Award	D	26,27		209.000		209.000
2016-12-08	2016-12-06	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	A - Award	D	26,27		28.000		28.000
2016-12-08	2016-12-06	4	Van Naarden Jacob	LOXO	Employee Stock Option (right to buy)	A - Award	D	26,27		74.000		74.000
2016-11-09	2016-11-07	4	Harr Steve	LOXO	Director Stock Option (right to buy)	A - Award	D	19,66		15.625		15.625
2016-09-09	2016-09-07	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		30,0000	-14.500	-435		45.982
2016-08-12	2016-08-10	4	Bonita David P See Footnotes	LOXO	Common Stock	S - Sale	I		26,9600	-447.857	-12.074		1.728.000
2016-08-12	2016-08-11	4	Flaherty Keith T.	LOXO	Common Stock	S - Sale	D		25,9978	-15.000	-390		60.482
2016-08-12	2016-08-10	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	S - Sale	I		26,9600	-447.857	-12.074		1.728.000
2016-06-13	2016-06-10	4	Bonita David P	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	ELMS STEVE	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-06-13	2016-06-10	4	Naider Avi Z.	LOXO	Director Stock Option (right to buy)	A - Award	D	24,18		7.812		7.812
2016-05-19	2016-05-17	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		21,5000	232.558	5.000		4.028.920
2015-12-18	2015-12-16	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	A - Award	D	31,69		142.000		142.000
2015-12-18	2015-12-16	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	A - Award	D	31,69		28.000		28.000
2015-12-15	2015-12-11	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		27,5000	200	6		3.796.362
2015-11-19	2015-11-17	4	Naider Avi Z.	LOXO	Common Stock	P - Purchase	D		26,5000	3.773	100		159.118
2015-11-19	2015-11-17	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		26,5000	265.000	7.022		3.796.182
2015-11-16	2015-11-13	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		27,4702	1.955	54		3.531.182
2015-11-16	2015-11-12	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		27,6523	76.714	2.121		3.529.207
2015-07-30		3	MAYLEBEN TIMOTHY M	LOXO	Common Stock		D						20.000
2015-07-30		3	MAYLEBEN TIMOTHY M	LOXO	Common Stock		D						20.000
2015-07-30	2015-07-28	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	ELMS STEVE	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	MAYLEBEN TIMOTHY M	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		15.625		15.625
2015-07-30	2015-07-28	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	Bonita David P	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	Kunkel Lori Anne	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	BARRETT M JAMES	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-07-30	2015-07-28	4	Naider Avi Z.	LOXO	Director Stock Option (right to buy)	A - Award	D	20,91		7.812		7.812
2015-05-01	2015-05-01	4	Burstein Jennifer	LOXO	Employee Stock Option (right to buy)	A - Award	D	11,35		50.000		50.000
2015-04-03	2015-04-02	4	GOLDSTEIN DOV A MD	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	7,14		-3.159		41.074
2015-04-03	2015-04-02	4	GOLDSTEIN DOV A MD	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-846		22.005
2015-04-03	2015-04-02	4	GOLDSTEIN DOV A MD	LOXO	Common Stock	M - Exercise	D		7,1360	3.159	23		65.873
2015-04-03	2015-04-02	4	GOLDSTEIN DOV A MD	LOXO	Common Stock	M - Exercise	D		3,6480	846	3		62.714
2015-04-03	2015-04-01	4	GOLDSTEIN DOV A MD	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	7,14		-31.595		44.233
2015-04-03	2015-04-01	4	GOLDSTEIN DOV A MD	LOXO	Employee Stock Option (right to buy)	M - Exercise	D	3,65		-7.617		22.851
2015-04-03	2015-04-01	4	GOLDSTEIN DOV A MD	LOXO	Common Stock	M - Exercise	D		7,1360	31.595	225		61.868
2015-04-03	2015-04-01	4	GOLDSTEIN DOV A MD	LOXO	Common Stock	M - Exercise	D		3,6480	7.617	28		30.273
2015-01-14	2015-01-12	4	Fuhrman Alan	LOXO	Director Stock Option (right to buy)	A - Award	D	11,35		15.625		15.625
2014-12-23	2014-12-19	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	13,67		12.500		12.500
2014-12-23	2014-12-19	4	Bilenker Joshua H.	LOXO	Employee Stock Option (right to buy)	A - Award	D	13,67		350.000		350.000
2014-12-23	2014-12-19	4	Low Jennifer A.	LOXO	Employee Stock Option (right to buy)	A - Award	D	13,67		100.000		100.000
2014-10-29		3	Kunkel Lori Anne	LOXO	Common Stock		D						53.680
2014-10-29		3	Kunkel Lori Anne	LOXO	Common Stock		D						53.680
2014-08-07	2014-08-06	4/A	ARRAY BIOPHARMA INC	LOXO	Series A-1 Convertible Preferred Stock	C - Conversion	D	0,00		-500.704		0
2014-08-07	2014-08-06	4/A	ARRAY BIOPHARMA INC	LOXO	Common Stock	C - Conversion	D			1.609.560			1.609.560
2014-08-06	2014-08-06	4	AISLING CAPITAL III LP	LOXO	Series B Convertible Preferred Stock	C - Conversion	D	0,00		-506.960		0
2014-08-06	2014-08-06	4	AISLING CAPITAL III LP	LOXO	Series A Convertible Preferred Stock	C - Conversion	D	0,00		-2.343.749		0
2014-08-06	2014-08-06	4	AISLING CAPITAL III LP	LOXO	Common Stock	P - Purchase	D		13,0000	413.077	5.370		3.452.493
2014-08-06	2014-08-06	4	AISLING CAPITAL III LP	LOXO	Common Stock	C - Conversion	D			2.850.709			3.039.416
2014-08-06	2014-08-06	4	ELMS STEVE Held directly by Aisling Capital III, LP	LOXO	Series B Preferred Stock	C - Conversion	I	0,00		-506.960		0
2014-08-06	2014-08-06	4	ELMS STEVE Held directly by Aisling Capital III, LP	LOXO	Series A Preferred Stock	C - Conversion	I	0,00		-2.343.749		0
2014-08-06	2014-08-06	4	ELMS STEVE Held by Aisling Capital III, LP	LOXO	Common Stock	P - Purchase	I		13,0000	413.077	5.370		3.452.493
2014-08-06	2014-08-06	4	ELMS STEVE Held by Aisling Capital III, LP	LOXO	Common Stock	C - Conversion	I			2.850.709			3.039.416
2014-08-06	2014-08-06	4	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Series B Preferred Stock	C - Conversion	I	0,00		-506.960		0
2014-08-06	2014-08-06	4	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Series A Preferred Stock	C - Conversion	I	0,00		-2.343.749		0
2014-08-06	2014-08-06	4	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Common Stock	P - Purchase	I		13,0000	413.077	5.370		3.452.493
2014-08-06	2014-08-06	4	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Common Stock	C - Conversion	I			2.850.709			3.039.416
2014-08-06	2014-08-06	4	Bonita David P	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-337.973		0
2014-08-06	2014-08-06	4	Bonita David P	LOXO	Series A Convertible Preferred Stock	C - Conversion	I			-1.562.499		0
2014-08-06	2014-08-06	4	Bonita David P	LOXO	Common Stock	P - Purchase	I		13,0000	275.385	3.580		2.175.857
2014-08-06	2014-08-06	4	Bonita David P	LOXO	Common Stock	C - Conversion	I			337.973			1.900.472
2014-08-06	2014-08-06	4	Bonita David P	LOXO	Common Stock	C - Conversion	I			1.562.499			1.562.499
2014-08-06	2014-08-06	4	New Enterprise Associates 14, L.P.	LOXO	Series B Convertible Preferred Stock	C - Conversion	D			-1.558.651		0
2014-08-06	2013-08-06	4	New Enterprise Associates 14, L.P.	LOXO	Common Stock	P - Purchase	D		13,0000	230.769	3.000		1.789.420
2014-08-06	2013-08-06	4	New Enterprise Associates 14, L.P.	LOXO	Common Stock	C - Conversion	D			1.558.651			1.558.651
2014-08-06	2014-08-06	4	BARRETT M JAMES See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	BARRETT M JAMES See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	BARRETT M JAMES See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	BARRIS PETER J See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	BARRIS PETER J See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	BARRIS PETER J See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	BASKETT FOREST See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	BASKETT FOREST See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	BASKETT FOREST See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	DRANT RYAN D See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	DRANT RYAN D See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	DRANT RYAN D See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	Florence Anthony A. Jr. See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	Florence Anthony A. Jr. See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	Florence Anthony A. Jr. See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	KERINS PATRICK J See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	KERINS PATRICK J See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	KERINS PATRICK J See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	KOLLURI KRISHNA KITTU See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	KOLLURI KRISHNA KITTU See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	KOLLURI KRISHNA KITTU See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	MOTT DAVID M See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	MOTT DAVID M See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	MOTT DAVID M See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	SANDELL SCOTT D See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	SANDELL SCOTT D See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	SANDELL SCOTT D See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	Viswanathan Ravi See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	Viswanathan Ravi See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	Viswanathan Ravi See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	Weller Harry R See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	Weller Harry R See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	Weller Harry R See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	Sonsini Peter W. See Note 2	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-1.558.651		0
2014-08-06	2014-08-06	4	Sonsini Peter W. See Note 2	LOXO	Common Stock	P - Purchase	I		13,0000	230.769	3.000		1.789.420
2014-08-06	2014-08-06	4	Sonsini Peter W. See Note 2	LOXO	Common Stock	C - Conversion	I			1.558.651			1.558.651
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations International Master Fund, L.P.	LOXO	Series B Preferred Stock	C - Conversion	I			-222.839		0
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations Fund, L.P.	LOXO	Series B Preferred Stock	C - Conversion	I			-279.051		0
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield International Master Fund, L.P.	LOXO	Common Stock	P - Purchase	I		13,0500	77.256	1.008		296.125
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield International Master Fund, L.P.	LOXO	Common Stock	P - Purchase	I		13,0000	218.869	2.845		218.869
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Partners, L.P.	LOXO	Common Stock	P - Purchase	I		13,0500	62.400	814		239.300
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Partners, L.P.	LOXO	Common Stock	P - Purchase	I		13,0000	176.900	2.300		176.900
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations International Master Fund, L.P.	LOXO	Common Stock	P - Purchase	I		13,0000	246.631	3.206		469.470
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations Fund, L.P.	LOXO	Common Stock	P - Purchase	I		13,0000	307.600	3.999		586.651
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations International Master Fund, L.P.	LOXO	Common Stock	C - Conversion	I			222.839			222.839
2014-08-06	2014-08-06	4	Flynn James E Through Deerfield Special Situations Fund, L.P.	LOXO	Common Stock	C - Conversion	I			279.051			279.051
2014-08-06	2014-08-06	4	Naider Avi Z.	LOXO	Series A Convertible Preferred Stock	C - Conversion	D	0,00		-62.499		0
2014-08-06	2014-08-06	4	Naider Avi Z.	LOXO	Common Stock	P - Purchase	D		13,0000	3.846	50		155.345
2014-08-06	2014-08-06	4	Naider Avi Z.	LOXO	Common Stock	C - Conversion	D			76.017			151.499
2014-08-06	2014-08-05	4	Naider Avi Z.	LOXO	Series B Convertible Preferred Stock	C - Conversion	D	0,00		-13.518		0
2014-08-06	2014-08-06	4	AI Loxo Holdings LLC	LOXO	Series B Convertible Preferred Stock	C - Conversion	D	0,00		-243.340		0
2014-08-06	2014-08-06	4	AI Loxo Holdings LLC	LOXO	Series A Convertible Preferred Stock	C - Conversion	D	0,00		-1.124.999		0
2014-08-06	2014-08-06	4	AI Loxo Holdings LLC	LOXO	Common Stock	C - Conversion	D			1.368.339			1.368.339
2014-08-06	2014-08-06	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Series B Convertible Preferred Stock	C - Conversion	I			-337.973		0
2014-08-06	2014-08-06	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Series A Convertible Preferred Stock	C - Conversion	I			-1.562.499		0
2014-08-06	2014-08-06	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	P - Purchase	I		13,0000	275.385	3.580		2.175.857
2014-08-06	2014-08-06	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	C - Conversion	I			337.973			1.900.472
2014-08-06	2014-08-06	4	ORBIMED ADVISORS LLC See Footnotes	LOXO	Common Stock	C - Conversion	I			1.562.499			1.562.499
2014-08-05	2014-07-31	4	ARRAY BIOPHARMA INC	LOXO	Series A-1 Convertible Preferred Stock	C - Conversion	D	0,00		-321.451		0
2014-08-05	2014-07-31	4	ARRAY BIOPHARMA INC	LOXO	Common Stock	C - Conversion	D			1.030.118			1.030.118
2014-08-01	2014-07-31	4	Bonita David P	LOXO	Director Stock Option (right to buy)	A - Award	D	13,00		15.625		15.625
2014-08-01	2014-07-31	4	ELMS STEVE	LOXO	Director Stock Option (right to buy)	A - Award	D	13,00		15.625		15.625
2014-08-01	2014-07-31	4	Flaherty Keith T.	LOXO	Director Stock Option (right to buy)	A - Award	D	13,00		15.625		15.625
2014-08-01	2014-07-31	4	BARRETT M JAMES	LOXO	Director Stock Option (right to buy)	A - Award	D	13,00		15.625		15.625
2014-08-01	2014-07-31	4	Naider Avi Z.	LOXO	Director Stock Option (right to buy)	A - Award	D	13,00		15.625		15.625
2014-07-31		3	Flaherty Keith T.	LOXO	Common Stock		D						150.964
2014-07-31		3	Flaherty Keith T.	LOXO	Common Stock		D						150.964
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	Purcell Dennis J	LOXO	Common Stock		D						377.414
2014-07-31		3	ELMS STEVE Held by Aisling Capital III, LP	LOXO	Common Stock		I						377.414
2014-07-31		3	ELMS STEVE Held by Aisling Capital III, LP	LOXO	Common Stock		I						377.414
2014-07-31		3	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Common Stock		I						400.070
2014-07-31		3	GOLDSTEIN DOV A MD	LOXO	Common Stock		D						234.019
2014-07-31		3	GOLDSTEIN DOV A MD Held by Aisling Capital III, LP	LOXO	Common Stock		I						400.070
2014-07-31		3	GOLDSTEIN DOV A MD	LOXO	Common Stock		D						234.019
2014-07-31		3	Naider Avi Z.	LOXO	Common Stock		D						150.964
2014-07-31		3	Naider Avi Z.	LOXO	Common Stock		D						150.964
2014-07-31		3	Bilenker Joshua H.	LOXO	Common Stock		D						377.414
2014-07-31		3	Bilenker Joshua H.	LOXO	Common Stock		D						377.414

Piața deschisă sau achiziția privată de titluri nederivate sau derivate

Piața deschisă sau vânzarea privată a titlurilor de valoare nederivate sau derivate

Acordarea, atribuirea sau alte achiziții de valori mobiliare de la companie (cum ar fi o opțiune)

Conversia derivatei

Vânzarea sau transferul de valori mobiliare înapoi către companie

Plata prețului de exercițiu sau a obligației fiscale folosind o parte din titlurile de valoare primite de la companie

Donarea de valori mobiliare de către sau către persoane din interior

Swap-uri de acțiuni și tranzacții similare de acoperire împotriva riscurilor

Exercitarea sau conversia titlurilor derivate primite de la companie (cum ar fi o opțiune)

O tranzacție raportată voluntar pe Formularul 4

Altele (însoțite de o notă de subsol care descrie tranzacția)

LOXO / Loxo Oncology, Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5