| Acțiuni Insider | 10.007.540 shares |
Scorul de sentimente din interior
Insider Sentiment Score găsește companiile cumpărate de persoane din interior.
Este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de persoane interne. Modelul de scoring folosește o combinație a numărului net de persoane din interior care cumpără în ultimele 90 de zile, totalul acțiunilor cumpărate ca procent din flota și totalul acțiunilor deținute de insider. Numărul variază de la 0 la 100, numerele mai mari indicând un nivel mai ridicat de acumulare pentru semenii săi, iar 50 fiind media.
Frecvența actualizării: zilnic
Scorul de sentiment al ofițerului
Scorul de sentiment al ofițerilor găsește companii cumpărate de ofițerii corporativi.
Prin definiție, Ofițerii Corporativi sunt Corporate Insiders, dar spre deosebire de unii dintre ceilalți Insiders (10% Acționari și Membri ai Consiliului de Administrație), Ofițerii lucrează zilnic pentru companie și își folosesc banii atunci când tranzacționează . (10% acționari și membri ai consiliului de administrație sunt adesea administratori de fonduri care gestionează banii altor persoane.) Ca atare, tranzacțiile privilegiate efectuate de către ofițeri sunt mult mai semnificative și ar trebui tratate în mod corespunzător.
La fel ca Scorul Sentimentului Insider, Scorul Sentimentului Ofițerului este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de ofițeri.
Frecvența actualizării: zilnic
Vedeți Top Picks Insiders, care oferă o listă a companiilor cu cel mai mare sentiment din interior.
Valori cheie ale insiderului
Acest card arată modul în care compania se clasifică de-a lungul diferitelor valori interne. Clasamentul percentilei arată cum se compară această companie cu alte companii de pe piețele din SUA. Clasamentele mai înalte indică situații mai bune.
De exemplu, este în general acceptat că cumpărarea din interior este un indicator pozitiv, astfel încât companiile cu mai multe achiziții din interior s-ar clasa mai sus decât companiile cu mai puține achiziții din interior (sau chiar vânzări din interior).
Numărul net de persoane din interior care cumpără (clasament)
N/A
Numărul net de persoane din interior care cumpără este numărul total de persoane din interior care cumpără minus numărul total de persoane din interior care au vândut în ultimele 90 de zile. Rangul percentilei este afișat aici (interval de la 0 la 100%).
Procent din flota cumpărată de persoane din interior (clasament)
N/A
Procent of Float Bought by Insiders este numărul total de acțiuni cumpărate de insiders minus numărul total de acțiuni vândute de insiders în ultimele 90 de zile, împărțit la flota totală și înmulțit cu 100.
Graficul privind tranzacțiile privilegiate
Alpine Immune Sciences, Inc. tranzacții privilegiate sunt prezentate în graficul următor. Insiders sunt ofițeri, directori sau investitori importanți într-o companie. În general, este în general ilegal ca persoanele din interior să facă tranzacții în companiile lor pe baza unor informații materiale, nepublice. Acest lucru nu înseamnă că este ilegal pentru ei să facă tranzacții în propriile companii. Cu toate acestea, ei trebuie să raporteze toate tranzacțiile către SEC printr-un Formular 4.
Lista de persoane din interior și valori de profitabilitate
Acest tabel prezintă lista persoanelor din interior cunoscute și este generată automat din dosarele dezvăluite SEC. Pe lângă nume, cel mai recent titlu și desemnarea directorului, a ofițerului sau a proprietarului în proporție de 10%, oferim cele mai recente dețineri divulgate. În plus, atunci când este posibil, oferim performanța comercială istorică pentru persoane din interior. Performanța comercială istorică este o medie ponderată a performanței tranzacțiilor reale de cumpărare pe piață deschisă efectuate de către insider. Pentru mai multe informații despre cum se calculează, urmăriți acest webinar YouTube.
See our leaderboard of most profitable insider traders.
| Insider | Profit mediu (%) | Acțiuni Deținut |
Despică Ajustat |
|---|
Report errors via our new Insider Auditing Tool
Înregistrări ale achizițiilor interne - Analiza profitului pe termen scurt
În această secțiune, analizăm profitabilitatea fiecărei achiziții neplanificate, pe piață deschisă, efectuată în ALPN / Alpine Immune Sciences, Inc.. Această analiză ajută la înțelegerea dacă persoana din interior generează în mod constant profituri anormale și merită urmărită. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .
Următorul tabel prezintă cele mai recente achiziții pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.
Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.
Înregistrări ale vânzărilor din interior - Analiza pierderilor pe termen scurt
În această secțiune, analizăm evitarea pierderilor pe termen scurt a fiecărei vânzări neplanificate, pe piață deschisă, efectuată în ALPN / Alpine Immune Sciences, Inc.. Un model consistent de evitare a pierderilor poate sugera că viitoarele tranzacții de vânzare pot prezice scăderi ale prețului. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .
Următorul tabel arată cele mai recente vânzări pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.
Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.
Istoricul tranzactiilor
Faceți clic pe pictograma link pentru a vedea istoricul complet al tranzacțiilor. Tranzacțiile raportate ca parte a unui plan de tranzacționare automată 10b5-1 vor avea un X în coloana marcată 10b-5.
| Fişier Data |
Comerț Data |
Formă | Insider | Ticker | Titlul de securitate | Cod | Direct | Exercițiu Preț |
Unitate Preț |
Unități Schimbat |
Valoare Schimbat (1K) |
Rămas Opțiuni |
Rămas Acțiuni |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-05-20 | 2024-05-20 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | -1.900 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | -50.000 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | -2.829.347 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -264.315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -2.416.181 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -1.735.544 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -6.582.380 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -31.200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -26.761 | 31.200 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -48.000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -296.163 | 48.000 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -96.000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -13.245 | 96.000 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -2.627.157 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -7.300 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -22.820 | 7.300 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -31.200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -102.192 | 31.200 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -264.315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -2.416.181 | 0 | ||||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,3300 | 13.377 | 85 | 344.163 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 3,2300 | 26.912 | 87 | 330.786 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 11,3100 | 22.593 | 256 | 303.874 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 161.492 | 105 | 281.281 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0,6500 | 37.267 | 24 | 119.789 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6,5100 | 3.126 | 20 | 82.522 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 13,2000 | 7.025 | 93 | 79.396 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,7600 | 10.000 | 48 | 133.392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 3,2300 | 38.078 | 123 | 123.392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4,0900 | 12.365 | 51 | 85.314 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 6,5100 | 25.000 | 163 | 72.949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 13,2000 | 9.845 | 130 | 47.949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 7,5500 | 13.245 | 100 | 109.245 | ||||
| 2024-05-10 | 2024-05-08 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 12,0700 | 22.820 | 275 | 30.120 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 398 | 2 | 57.961 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 18.286 | 59 | 57.563 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 164 | 2 | 39.277 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 857 | 6 | 39.113 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,2000 | 7.055 | 93 | 38.256 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 7,5500 | 1 | 0 | 31.201 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 64,5700 | -19 | -1 | 2.829.347 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 0,0010 | 1.200.000 | 1 | 2.829.366 | ||||
| 2024-04-05 | 3 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 7.300 | ||||||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 25,0000 | -44.000 | -1.100 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11,3100 | 44.000 | 498 | 44.000 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,3121 | -73.764 | -1.646 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 73.764 | 480 | 73.764 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22,0000 | -236 | -5 | 0 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6,5100 | 236 | 2 | 236 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 12,7400 | 1.234.636 | 15.729 | 6.582.380 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,7400 | 1.234.636 | 15.729 | 6.582.380 | ||||
| 2024-01-16 | 2024-01-11 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 2.416.181 | ||||
| 2024-01-16 | 2024-01-11 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 2.416.181 | ||||
| 2024-01-05 | 2024-01-04 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 48.000 | 72.371 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 96.000 | 96.000 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 31.200 | 31.200 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | DURAND REMY | ALPN | Common Stock | D | 31.200 | 38.104 | ||||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 19,6500 | -48.264 | -948 | 2.627.157 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 12,7400 | 74.441 | 948 | 2.675.421 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0413 | -1.016 | -20 | 0 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 1.016 | 1 | 1.016 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | -139.166 | -2.550 | 264.315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18,3200 | -1.195.683 | -21.905 | 2.270.930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | -3.128 | -62 | 403.481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,8200 | -26.872 | -533 | 3.466.613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | -18.922 | -378 | 406.609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19,9600 | -162.576 | -3.245 | 3.493.485 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | -139.166 | -2.550 | 264.315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18,3200 | -1.195.683 | -21.905 | 2.270.930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | -3.128 | -62 | 403.481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,8200 | -26.872 | -533 | 3.466.613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | -18.922 | -378 | 406.609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19,9600 | -162.576 | -3.245 | 3.493.485 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0425 | -29.573 | -593 | 0 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 29.573 | 19 | 29.573 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,2245 | -24.486 | -495 | 0 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,6500 | 22.084 | 14 | 24.486 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2.402 | 1 | 2.402 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,4255 | -37.825 | -773 | 0 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 37.825 | 17 | 37.825 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,2087 | -15.213 | -292 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 15.213 | 76 | 15.213 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20,0099 | -2.402 | -48 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 2.402 | 1 | 2.402 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0017 | -1.800 | -34 | 0 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 1.800 | 9 | 1.800 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0888 | -45.387 | -866 | 0 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 45.387 | 228 | 45.387 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19,0005 | -11.600 | -220 | 0 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5,0200 | 11.600 | 58 | 11.600 | ||||
| 2023-12-13 | 2023-12-11 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 12,7400 | 145.251 | 1.850 | 1.629.366 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | -8.613 | -149 | 0 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0,4500 | 8.613 | 4 | 8.613 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,3155 | -32.450 | -562 | 0 | ||||
| 2023-12-12 | 2023-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,2648 | -68.870 | -1.189 | 32.450 | ||||
| 2023-12-12 | 2023-12-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17,0799 | -8.067 | -138 | 101.320 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0797 | -6.446 | -104 | 0 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 6.446 | 21 | 6.446 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0139 | -418 | -7 | 0 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 418 | 1 | 418 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0584 | -63.947 | -1.027 | 0 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 63.947 | 207 | 63.947 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0000 | -700 | -11 | 0 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 700 | 2 | 700 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12,5000 | 375.000 | 4.688 | 1.735.544 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Decheng Capital Global Healthcare Fund (Master), LP | ALPN | Common Stock | D | 12,5000 | 375.000 | 4.688 | 1.735.544 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16,0281 | -18.003 | -289 | 0 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3,2300 | 10.989 | 35 | 18.003 | ||||
| 2023-04-27 | 3 | DURAND REMY | ALPN | Common Stock | D | 6.904 | ||||||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 1.360.544 | 10.000 | 1.360.544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7,3500 | 639.456 | 4.700 | 5.347.744 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | I | 7,3500 | 1.360.544 | 10.000 | 1.360.544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 7,3500 | 639.456 | 4.700 | 5.347.744 | ||||
| 2022-07-19 | 2022-07-15 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 0,4500 | 20.063 | 9 | 238.126 | ||||
| 2022-02-15 | 2022-02-11 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 7,1006 | 112.665 | 800 | 1.484.115 | ||||
| 2022-01-06 | 2022-01-04 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,30 | 215.000 | 215.000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,30 | 215.000 | 215.000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,30 | 112.500 | 112.500 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2021-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13,9162 | -17.013 | -237 | 7.014 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,89 | 10.000 | 10.000 | |||||
| 2021-09-27 | 2021-09-23 | 4/A | Peetz Christopher Christopher Peetz and Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1.900 | 19 | 1.900 | ||||
| 2021-09-27 | 2021-09-23 | 4/A | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15.000 | 151 | 50.000 | ||||
| 2021-09-24 | 2021-09-23 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10,1700 | 1.900 | 19 | 1.900 | ||||
| 2021-09-24 | 2021-09-23 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10,0769 | 15.000 | 151 | 50.000 | ||||
| 2021-09-23 | 2021-09-21 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 9,7966 | 10.000 | 98 | 35.000 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 425.531 | 4.000 | 425.531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9,4000 | 585.106 | 5.500 | 3.656.061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 9,4000 | 1.542.553 | 14.500 | 4.708.288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 425.531 | 4.000 | 425.531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9,4000 | 585.106 | 5.500 | 3.656.061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0076 | -45.262 | -453 | 109.387 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9,4000 | -400.000 | -3.760 | 2.600.980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 9,4000 | 1.542.553 | 14.500 | 4.708.288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 0,00 | 1.200.000 | 1.200.000 | |||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | -1.200.000 | 1.371.450 | ||||||
| 2021-09-17 | 2021-09-16 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0024 | -6.768 | -68 | 154.649 | ||||
| 2021-09-17 | 2021-09-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0000 | -3.484 | -35 | 161.417 | ||||
| 2021-06-29 | 2021-06-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0005 | -3.479 | -35 | 164.901 | ||||
| 2021-06-29 | 2021-06-25 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0143 | -9.473 | -95 | 168.380 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Goldberg Zelanna | ALPN | Stock Option (Right to buy) | D | 10,29 | 160.000 | 160.000 | |||||
| 2021-05-21 | 2021-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0006 | -1.221 | -18 | 177.853 | ||||
| 2021-05-21 | 2021-05-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15,0283 | -50.965 | -766 | 179.074 | ||||
| 2021-05-14 | 2021-05-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,5169 | -10.000 | -115 | 230.039 | ||||
| 2021-05-14 | 2021-05-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,6842 | -10.000 | -117 | 240.039 | ||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | -7.650 | 0 | |||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 3,6233 | 7.650 | 28 | 218.063 | ||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | -7.650 | 0 | |||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 4,0900 | 7.650 | 31 | 210.413 | ||||
| 2021-04-15 | 2021-04-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,5200 | -10.000 | -105 | 250.039 | ||||
| 2021-04-15 | 2021-04-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10,0714 | -10.000 | -101 | 260.039 | ||||
| 2021-03-08 | 2021-03-05 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,9875 | -10.000 | -130 | 270.039 | ||||
| 2021-03-08 | 2021-03-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,0108 | -10.000 | -130 | 280.039 | ||||
| 2021-02-03 | 2021-02-02 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11,7381 | -10.000 | -117 | 290.039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13,2029 | -7.021 | -93 | 300.039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,0738 | -2.979 | -36 | 307.060 | ||||
| 2021-01-06 | 2021-01-05 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13,20 | 150.000 | 150.000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13,20 | 255.000 | 255.000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13,20 | 120.000 | 120.000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13,45 | 7.650 | 7.650 | |||||
| 2021-01-04 | 2020-12-31 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 12,6000 | -3.923 | -49 | 24.371 | ||||
| 2021-01-04 | 2020-12-31 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12,6000 | -11.123 | -140 | 310.039 | ||||
| 2021-01-04 | 2020-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 12,6000 | -2.258 | -28 | 24.027 | ||||
| 2020-12-30 | 2020-12-28 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 14,2500 | -600.000 | -8.550 | 3.070.955 | ||||
| 2020-12-30 | 2020-12-28 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 14,2500 | -600.000 | -8.550 | 3.070.955 | ||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 260.528 | 321.162 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993.801 | 3.000.980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 181.024 | 202.763 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993.801 | 3.000.980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | -993.801 | 3.000.980 | ||||||
| 2020-12-11 | 2020-12-10 | 4 | Hernday Natasha | ALPN | Stock Option (right to buy) | D | 11,07 | 15.000 | 15.000 | |||||
| 2020-11-23 | 2020-11-19 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 8,0300 | 10.000 | 80 | 25.000 | ||||
| 2020-07-09 | 2020-07-08 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 7,20 | 50.000 | 50.000 | |||||
| 2020-07-01 | 2020-06-30 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 9,7100 | -3.923 | -38 | 28.294 | ||||
| 2020-07-01 | 2020-06-30 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 9,7100 | -8.227 | -80 | 60.634 | ||||
| 2020-07-01 | 2020-06-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 9,7100 | -2.258 | -22 | 26.285 | ||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 3,23 | 270.000 | 270.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 67.569 | 68.861 | ||||||
| 2020-01-27 | 2019-12-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5.000 | 1.292 | ||||||
| 2020-01-27 | 2019-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5.000 | 6.292 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 3,23 | 108.000 | 108.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 32.217 | 32.217 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 3,23 | 102.000 | 102.000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Common Stock | D | 18.543 | 28.543 | ||||||
| 2020-01-06 | 2020-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 3,62 | 7.650 | 7.650 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 4,9500 | 10.000 | 50 | 10.000 | ||||
| 2019-02-12 | 2019-02-08 | 4 | TIGER MANAGEMENT L.L.C. | ALPN | Common Stock | I | 5,8498 | -25.000 | -146 | 137.728 | ||||
| 2019-02-08 | 2019-02-06 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 25.000 | 25.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 6,51 | 200.000 | 200.000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 6,51 | 75.000 | 75.000 | |||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6.331.470 | ||||||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Stock Option (right to buy) | D | 5,70 | 7.650 | 7.650 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Warrant (right to buy) | I | 12,74 | 5,3700 | 1.234.636 | 6.630 | 1.234.636 | |||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 5,3700 | 3.165.735 | 17.000 | 3.165.735 | ||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145.251 | 145.251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 3.670.955 | ||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145.251 | 145.251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 3.670.955 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2018-05-21 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -6.000 | 11.292 | ||||||
| 2019-01-22 | 2018-05-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3.000 | 17.292 | ||||||
| 2019-01-22 | 2018-05-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3.000 | 20.292 | ||||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | D | 12,74 | 74.441 | 74.441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 5,3700 | 190.875 | 1.025 | 3.994.781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | I | 12,74 | 145.251 | 145.251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 5,3700 | 372.439 | 2.000 | 2.571.450 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 12,74 | 145.251 | 145.251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 5,3700 | 372.439 | 2.000 | 2.571.450 | ||||
| 2019-01-04 | 2019-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 4,09 | 7.650 | 7.650 | |||||
| 2018-10-02 | 2018-09-28 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 6,33 | 250.000 | 250.000 | |||||
| 2018-08-08 | 2018-08-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6,81 | 150.000 | 150.000 | |||||
| 2018-04-24 | 2018-04-20 | 4 | Peetz Christopher | ALPN | Stock Option (right to buy) | D | 7,91 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 11,31 | 70.000 | 70.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 11,31 | 45.000 | 45.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 11,31 | 65.000 | 65.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 11,31 | 25.000 | 25.000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 11,31 | 7.650 | 7.650 | |||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4.398.022 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7.607.812 | ||||||||
| 2017-07-26 | 2017-07-24 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 3.298.516 | 3.298.516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 208.916 | 208.916 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 300.624 | 300.624 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 51.242 | 51.242 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3.803.906 | 3.803.906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 23.292 | 23.292 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Aidan J. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Simon P. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Noah M. Gold | ALPN | Common Stock | I | 24.845 | 24.845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Employee Stock Option (right to buy) | D | 0,45 | 90.063 | 90.063 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3.803.906 | 3.803.906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 21.739 | 21.739 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Nathaniel Graham Venkatesan | ALPN | Common Stock | I | 18.633 | 18.633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Reid Coleman Venkatesan | ALPN | Common Stock | I | 18.633 | 18.633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Rickey James Paul | ALPN | Employee Stock Option (right to buy) | D | 5,02 | 74.535 | 74.535 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Topper James N See Footnotes | ALPN | Common Stock | I | 2.199.011 | 2.199.011 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 3.298.516 | 3.298.516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 37.267 | 37.267 | |||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0,65 | 161.492 | 161.492 | |||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 1.715 | 4 | 201.811 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 6.359 | 14 | 717.089 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2500 | 9.732 | 22 | 1.109.258 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 3.673 | 8 | 200.096 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 13.046 | 30 | 710.730 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2813 | 20.181 | 46 | 1.099.526 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 3.920 | 9 | 196.423 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 12.624 | 29 | 697.684 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2906 | 19.206 | 44 | 1.079.345 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 2.727 | 6 | 192.503 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 10.023 | 23 | 685.060 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2470 | 15.350 | 34 | 1.060.139 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 1.805 | 4 | 189.776 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 6.903 | 16 | 675.037 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2957 | 10.192 | 23 | 1.044.789 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 1.124 | 3 | 187.971 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 4.223 | 10 | 668.134 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3000 | 6.253 | 14 | 1.034.597 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 2.909 | 7 | 186.847 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 10.541 | 24 | 663.911 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2998 | 16.436 | 38 | 1.028.344 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 5.510 | 13 | 183.938 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 6.897 | 16 | 653.370 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2987 | 24.965 | 57 | 1.011.908 | ||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.630.471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2.310.352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1.870.417 | ||||||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 675 | 2 | 178.428 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 2.565 | 6 | 646.473 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3429 | 3.794 | 9 | 986.943 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 6.217 | 15 | 177.753 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 22.092 | 52 | 643.908 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,3457 | 33.691 | 79 | 983.149 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 3.929 | 9 | 171.536 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 14.274 | 33 | 621.816 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2,2879 | 21.797 | 50 | 949.458 | ||||
| 2017-05-11 | 2017-05-08 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2800 | 15.000 | 34 | 60.000 | ||||
| 2017-05-10 | 2017-05-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3400 | 5.000 | 12 | 45.000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | TROHA JANICE | NVLS | Common Stock | D | 2,3400 | 10.000 | 23 | 10.000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,3000 | 20.000 | 46 | 40.000 | ||||
| 2017-05-08 | 2017-05-04 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2,2600 | 10.000 | 23 | 20.000 | ||||
| 2017-01-23 | 2017-01-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200.000 | 200.000 | |||||
| 2017-01-23 | 2017-01-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 2,21 | 200.000 | 200.000 | |||||
| 2017-01-05 | 2017-01-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 2,2700 | -6.687 | -15 | 11.368 | ||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.056 | 162.501 | |||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.055 | 18.055 | ||||||
| 2016-12-05 | 2016-12-02 | 4 | Carruthers R Michael | NVLS | Common Stock | D | 2,0940 | 24.000 | 50 | 24.000 | ||||
| 2016-10-05 | 2016-10-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 7,9600 | -5.820 | -46 | 12.236 | ||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.056 | 180.556 | |||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.056 | 18.056 | ||||||
| 2016-09-14 | 2016-09-12 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110.000 | 110.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | SEKHRI PAUL J | NVLS | Stock Option (Right to Buy) | D | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Flynn James E Through Deerfield Management Company, L.P. | NVLS | Stock Option (right to buy) | I | 7,77 | 12.300 | 12.300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 7,77 | 110.000 | 110.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 7,77 | 250.000 | 250.000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Rodman David Malcom | NVLS | Stock Option (Right to Buy) | D | 7,77 | 100.000 | 100.000 | |||||
| 2016-07-06 | 2016-07-05 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 4,6600 | -5.950 | -28 | 12.105 | ||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0,00 | -18.055 | 198.612 | |||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18.055 | 18.055 | ||||||
| 2016-06-17 | 2016-06-16 | 4 | Congleton Jon | NVLS | Common Stock | D | 3,8689 | 5.000 | 19 | 20.000 | ||||
| 2016-03-25 | 2016-03-24 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,2169 | 5.000 | 21 | 15.000 | ||||
| 2016-03-23 | 2016-03-22 | 4 | Congleton Jon | NVLS | Common Stock | D | 4,3815 | 5.000 | 22 | 10.000 | ||||
| 2015-12-14 | 2015-12-11 | 4 | Congleton Jon | NVLS | Common Stock | D | 8,1000 | 5.000 | 40 | 5.000 | ||||
| 2015-12-11 | 2015-12-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 8,1000 | 10.000 | 81 | 10.000 | ||||
| 2015-09-15 | 2015-09-11 | 4 | Shoemaker Steven | NVLS | Stock Option (Right to Buy) | D | 15,28 | 39.700 | 39.700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 15,28 | 55.400 | 55.400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Gabriel Sherif | NVLS | Stock Option (Right to Buy) | D | 15,28 | 24.700 | 24.700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 15,28 | 121.100 | 121.100 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 15,28 | 65.400 | 65.400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 15,28 | 7.650 | 7.650 | |||||
| 2015-07-20 | 2015-07-16 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 17,49 | 11.475 | 11.475 | |||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 2 Preferred Stock | I | -936.839 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 2 Preferred Stock | I | -817.541 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 2 Preferred Stock | I | -85.962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -54.385 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -385.962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 1 Preferred Stock | I | -1.243.423 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 1 Preferred Stock | I | -1.085.085 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 1 Preferred Stock | I | -1.401.003 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -869.667 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -2.013.613 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 14,0000 | 77.539 | 1.086 | 832.216 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 14,0000 | 67.666 | 947 | 726.242 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 14,0000 | 104.795 | 1.467 | 1.124.740 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 324.278 | 754.677 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 282.984 | 658.576 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 29.755 | 647.152 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 18.825 | 402.062 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 133.597 | 1.019.945 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 430.399 | 430.399 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 375.592 | 375.592 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 484.944 | 617.397 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 301.027 | 383.237 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 696.993 | 886.348 | ||||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Series 2 Convertible Preferred Stock | I | 2,85 | -364.358 | 0 | |||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 14,0000 | 200.000 | 2.800 | 564.358 | ||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 364.358 | 364.358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -1.052.631 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Common stock | D | 364.358 | 364.358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -818.714 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 283.390 | 320.990 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7479 | 5.500 | 81 | 37.600 | ||||
| 2015-06-23 | 2015-06-19 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,6659 | 11.700 | 172 | 32.100 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Series 2 convertible preferred stock | D | 14,00 | -303.631 | 0 | |||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 303.631 | 4.251 | 329.780 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Series 1 convertible preferred stock | D | -2.200.404 | 0 | ||||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 761.649 | 1.557.228 | ||||||
| 2015-06-19 | 2015-06-18 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6.200 | 91 | 20.400 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,7500 | 6.700 | 99 | 14.200 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14,0000 | 7.500 | 105 | 7.500 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14,0000 | 26.149 | 366 | 26.149 | ||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1.301.830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1.301.830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1.301.830 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1.591.158 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1.591.158 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66.558 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66.558 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4.326 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486.233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593.380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536.475 |
P
Piața deschisă sau achiziția privată de titluri nederivate sau derivate
S
Piața deschisă sau vânzarea privată a titlurilor de valoare nederivate sau derivate
A
Acordarea, atribuirea sau alte achiziții de valori mobiliare de la companie (cum ar fi o opțiune)
C
Conversia derivatei
D
Vânzarea sau transferul de valori mobiliare înapoi către companie
F
Plata prețului de exercițiu sau a obligației fiscale folosind o parte din titlurile de valoare primite de la companie
G
Donarea de valori mobiliare de către sau către persoane din interior
K
Swap-uri de acțiuni și tranzacții similare de acoperire împotriva riscurilor
M
Exercitarea sau conversia titlurilor derivate primite de la companie (cum ar fi o opțiune)
V
O tranzacție raportată voluntar pe Formularul 4
J
Altele (însoțite de o notă de subsol care descrie tranzacția)
