| Acțiuni Insider | 7.464.864 shares |
Scorul de sentimente din interior
Insider Sentiment Score găsește companiile cumpărate de persoane din interior.
Este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de persoane interne. Modelul de scoring folosește o combinație a numărului net de persoane din interior care cumpără în ultimele 90 de zile, totalul acțiunilor cumpărate ca procent din flota și totalul acțiunilor deținute de insider. Numărul variază de la 0 la 100, numerele mai mari indicând un nivel mai ridicat de acumulare pentru semenii săi, iar 50 fiind media.
Frecvența actualizării: zilnic
Scorul de sentiment al ofițerului
Scorul de sentiment al ofițerilor găsește companii cumpărate de ofițerii corporativi.
Prin definiție, Ofițerii Corporativi sunt Corporate Insiders, dar spre deosebire de unii dintre ceilalți Insiders (10% Acționari și Membri ai Consiliului de Administrație), Ofițerii lucrează zilnic pentru companie și își folosesc banii atunci când tranzacționează . (10% acționari și membri ai consiliului de administrație sunt adesea administratori de fonduri care gestionează banii altor persoane.) Ca atare, tranzacțiile privilegiate efectuate de către ofițeri sunt mult mai semnificative și ar trebui tratate în mod corespunzător.
La fel ca Scorul Sentimentului Insider, Scorul Sentimentului Ofițerului este rezultatul unui model cantitativ sofisticat, multifactorial, care identifică companiile cu cele mai înalte niveluri de acumulare de ofițeri.
Frecvența actualizării: zilnic
Vedeți Top Picks Insiders, care oferă o listă a companiilor cu cel mai mare sentiment din interior.
Valori cheie ale insiderului
Acest card arată modul în care compania se clasifică de-a lungul diferitelor valori interne. Clasamentul percentilei arată cum se compară această companie cu alte companii de pe piețele din SUA. Clasamentele mai înalte indică situații mai bune.
De exemplu, este în general acceptat că cumpărarea din interior este un indicator pozitiv, astfel încât companiile cu mai multe achiziții din interior s-ar clasa mai sus decât companiile cu mai puține achiziții din interior (sau chiar vânzări din interior).
Numărul net de persoane din interior care cumpără (clasament)
Numărul net de persoane din interior care cumpără este numărul total de persoane din interior care cumpără minus numărul total de persoane din interior care au vândut în ultimele 90 de zile. Rangul percentilei este afișat aici (interval de la 0 la 100%).
Procent din flota cumpărată de persoane din interior (clasament)
Procent of Float Bought by Insiders este numărul total de acțiuni cumpărate de insiders minus numărul total de acțiuni vândute de insiders în ultimele 90 de zile, împărțit la flota totală și înmulțit cu 100.
Graficul privind tranzacțiile privilegiate
Sierra Oncology Inc tranzacții privilegiate sunt prezentate în graficul următor. Insiders sunt ofițeri, directori sau investitori importanți într-o companie. În general, este în general ilegal ca persoanele din interior să facă tranzacții în companiile lor pe baza unor informații materiale, nepublice. Acest lucru nu înseamnă că este ilegal pentru ei să facă tranzacții în propriile companii. Cu toate acestea, ei trebuie să raporteze toate tranzacțiile către SEC printr-un Formular 4.
Lista de persoane din interior și valori de profitabilitate
Acest tabel prezintă lista persoanelor din interior cunoscute și este generată automat din dosarele dezvăluite SEC. Pe lângă nume, cel mai recent titlu și desemnarea directorului, a ofițerului sau a proprietarului în proporție de 10%, oferim cele mai recente dețineri divulgate. În plus, atunci când este posibil, oferim performanța comercială istorică pentru persoane din interior. Performanța comercială istorică este o medie ponderată a performanței tranzacțiilor reale de cumpărare pe piață deschisă efectuate de către insider. Pentru mai multe informații despre cum se calculează, urmăriți acest webinar YouTube.
See our leaderboard of most profitable insider traders.
| Insider | Profit mediu (%) | Acțiuni Deținut |
Despică Ajustat |
|---|
Report errors via our new Insider Auditing Tool
Înregistrări ale achizițiilor interne - Analiza profitului pe termen scurt
În această secțiune, analizăm profitabilitatea fiecărei achiziții neplanificate, pe piață deschisă, efectuată în SRRA / Sierra Oncology Inc. Această analiză ajută la înțelegerea dacă persoana din interior generează în mod constant profituri anormale și merită urmărită. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .
Următorul tabel prezintă cele mai recente achiziții pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.
Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.
Înregistrări ale vânzărilor din interior - Analiza pierderilor pe termen scurt
În această secțiune, analizăm evitarea pierderilor pe termen scurt a fiecărei vânzări neplanificate, pe piață deschisă, efectuată în SRRA / Sierra Oncology Inc. Un model consistent de evitare a pierderilor poate sugera că viitoarele tranzacții de vânzare pot prezice scăderi ale prețului. Această analiză este pentru un an după fiecare tranzacție și rezultatele sunt teoretice .
Următorul tabel arată cele mai recente vânzări pe piața deschisă care nu făceau parte dintr-un plan de tranzacționare automată.
| Data tranzacției | Insider | Raportat Acțiuni |
Raportat Preț |
Ajustat Acțiuni |
Ajustat Preț |
Baza costurilor | Zile pentru Min |
Pret la Min |
Pierdere maximă Evitat ($) |
Pierdere maximă Evitat (%) |
|---|---|---|---|---|---|---|---|
| Nu se cunosc tranzacții neplanificate pe piața deschisă pentru acest insider |
Prețul ajustat este prețul ajustat în divizarea. Acțiunile ajustate reprezintă acțiunile ajustate în funcție de divizarea.
Istoricul tranzactiilor
Faceți clic pe pictograma link pentru a vedea istoricul complet al tranzacțiilor. Tranzacțiile raportate ca parte a unui plan de tranzacționare automată 10b5-1 vor avea un X în coloana marcată 10b-5.
| Fişier Data |
Comerț Data |
Formă | Insider | Ticker | Titlul de securitate | Cod | Direct | Exercițiu Preț |
Unitate Preț |
Unități Schimbat |
Valoare Schimbat (1K) |
Rămas Opțiuni |
Rămas Acțiuni |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-07-01 | 2022-07-01 | 4 | Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P. | SRRA | Common Stock | I | 55,0000 | -431.947 | -23.757 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Vivo Opportunity, LLC By: Vivo Opportunity Fund Holdings, L.P. | SRRA | Common Stock | I | 55,0000 | -2.735.853 | -150.472 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 55,0000 | -161.712 | -8.894 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | ORBIMED ADVISORS LLC See footnotes | SRRA | Common Stock | I | 55,0000 | -226.704 | -12.469 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | ORBIMED ADVISORS LLC See footnotes | SRRA | Common Stock | I | 55,0000 | -226.704 | -12.469 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | ORBIMED ADVISORS LLC See footnotes | SRRA | Common Stock | I | 55,0000 | -1.511.362 | -83.125 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Ashiya Mona See footnotes | SRRA | Common Stock | I | 55,0000 | -226.704 | -12.469 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Ashiya Mona See footnotes | SRRA | Common Stock | I | 55,0000 | -226.704 | -12.469 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Ashiya Mona See footnotes | SRRA | Common Stock | I | 55,0000 | -1.511.362 | -83.125 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Aggarwal Gaurav By: Vivo Opportunity Fund Holdings, L.P. | SRRA | Common Stock | I | 55,0000 | -2.735.853 | -150.472 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Klencke Barbara By spouse | SRRA | Common Stock | I | 55,0000 | -5.000 | -275 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Klencke Barbara | SRRA | Common Stock | D | 55,0000 | -10.000 | -550 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Sinclair Andrew See footnotes | SRRA | Common Stock, $0.001 par value | I | 55,0000 | -1.314.127 | -72.277 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Allen Andrew R | SRRA | Common Stock | D | 55,0000 | -1.650 | -91 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | Collard Craig A | SRRA | Common Stock | D | 55,0000 | -13.500 | -742 | 0 | ||||
| 2022-07-01 | 2022-07-01 | 4 | DILLY STEPHEN GEORGE | SRRA | Common Stock | D | 55,0000 | -5.000 | -275 | 0 | ||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 840 | 8.015 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 252 | 2.404 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 588 | 5.611 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 7.175 | 7.175 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 2.152 | 2.152 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 5.023 | 5.023 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | -1.964.771 | 0 | ||||||
| 2022-04-29 | 2022-04-27 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | -175.000 | 0 | ||||||
| 2022-04-07 | 2022-04-06 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 6.347 | 0 | |||||
| 2022-04-07 | 2022-04-06 | 4 | Turner William D. | SRRA | Common Stock | D | 37,2474 | -6.347 | -236 | 0 | ||||
| 2022-04-07 | 2022-04-06 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 6.347 | 76 | 6.347 | ||||
| 2022-04-07 | 2022-04-05 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 100 | 0 | |||||
| 2022-04-07 | 2022-04-05 | 4 | Turner William D. | SRRA | Common Stock | D | 37,0900 | -100 | -4 | 0 | ||||
| 2022-04-07 | 2022-04-05 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 100 | 1 | 100 | ||||
| 2022-04-04 | 2022-04-04 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 13,04 | 2.000 | 0 | |||||
| 2022-04-04 | 2022-04-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 35,1384 | -2.000 | -70 | 0 | ||||
| 2022-04-04 | 2022-04-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 13,0400 | 2.000 | 26 | 2.000 | ||||
| 2022-03-22 | 2022-03-18 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 100 | 0 | |||||
| 2022-03-22 | 2022-03-18 | 4 | Turner William D. | SRRA | Common Stock | D | 37,0500 | -100 | -4 | 0 | ||||
| 2022-03-22 | 2022-03-18 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 100 | 1 | 100 | ||||
| 2022-03-17 | 2022-03-17 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 3.453 | 0 | |||||
| 2022-03-17 | 2022-03-17 | 4 | Turner William D. | SRRA | Common Stock | D | 37,0558 | -3.453 | -128 | 0 | ||||
| 2022-03-17 | 2022-03-17 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 3.453 | 42 | 3.453 | ||||
| 2022-03-14 | 2022-03-14 | 4 | DILLY STEPHEN GEORGE | SRRA | Stock Option (Right to Buy) | D | 31,54 | 165.000 | 165.000 | |||||
| 2022-03-14 | 2022-03-14 | 4 | Jagpal Sukhi | SRRA | Stock Option (Right to Buy) | D | 31,54 | 50.000 | 50.000 | |||||
| 2022-03-14 | 2022-03-14 | 4 | Klencke Barbara | SRRA | Stock Option (Right to Buy) | D | 31,54 | 50.000 | 50.000 | |||||
| 2022-03-14 | 2022-03-14 | 4 | Norrett Kevin | SRRA | Stock Option (Right to Buy) | D | 31,54 | 35.000 | 35.000 | |||||
| 2022-03-14 | 2022-03-14 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 31,54 | 35.000 | 35.000 | |||||
| 2022-03-14 | 2022-03-14 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 31,54 | 35.000 | 35.000 | |||||
| 2022-03-04 | 2022-03-04 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 13,04 | 2.000 | 0 | |||||
| 2022-03-04 | 2022-03-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 30,5981 | -2.000 | -61 | 0 | ||||
| 2022-03-04 | 2022-03-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 13,0400 | 2.000 | 26 | 2.000 | ||||
| 2022-02-08 | 2022-02-07 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 10.000 | 0 | |||||
| 2022-02-08 | 2022-02-07 | 4 | Turner William D. | SRRA | Common Stock | D | 32,3225 | -10.000 | -323 | 0 | ||||
| 2022-02-08 | 2022-02-07 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 10.000 | 120 | 10.000 | ||||
| 2022-02-04 | 2022-02-04 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 13,04 | 2.000 | 0 | |||||
| 2022-02-04 | 2022-02-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 29,7800 | -2.000 | -60 | 0 | ||||
| 2022-02-04 | 2022-02-04 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 13,0400 | 2.000 | 26 | 2.000 | ||||
| 2022-02-02 | 2022-02-02 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 27,0000 | 175.000 | 4.725 | 175.000 | ||||
| 2022-02-02 | 2022-02-02 | 4 | Richardson Joshua | SRRA | Common Stock | I | 27,0000 | 175.000 | 4.725 | 175.000 | ||||
| 2022-02-02 | 3 | Longitude Prime Fund, L.P. | SRRA | Common Stock | I | 175.000 | ||||||||
| 2022-02-01 | 2022-01-31 | 4 | Sinclair Andrew See footnotes | SRRA | Common Stock, $0.001 par value | I | 27,0000 | 150.000 | 4.050 | 1.314.127 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Sinclair Andrew See footnotes | SRRA | Series B Warrants (right to buy) | I | 13,20 | -287.471 | 0 | |||||
| 2022-02-01 | 2022-01-28 | 4 | Sinclair Andrew See footnotes | SRRA | Common Stock, $0.001 par value | I | 13,2000 | 287.471 | 3.795 | 1.164.127 | ||||
| 2022-02-01 | 2022-01-31 | 4 | Abingworth LLP | SRRA | Common Stock, $0.001 par value | I | 27,0000 | 150.000 | 4.050 | 1.314.127 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Abingworth LLP | SRRA | Series B Warrants (right to buy) | I | 13,20 | -287.471 | 0 | |||||
| 2022-02-01 | 2022-01-28 | 4 | Abingworth LLP | SRRA | Common Stock, $0.001 par value | I | 13,2000 | 287.471 | 3.795 | 1.164.127 | ||||
| 2022-01-31 | 2022-01-31 | 4 | Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P. | SRRA | Common Stock | I | 27,0000 | 800.000 | 21.600 | 2.735.853 | ||||
| 2022-01-31 | 2022-01-31 | 4 | Aggarwal Gaurav By Vivo Opportunity Fund, L.P. | SRRA | Common Stock | I | 27,0000 | 800.000 | 21.600 | 2.735.853 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes | SRRA | Series B Warrants | I | 13,20 | -56.244 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes | SRRA | Series B Warrants | I | 13,20 | -56.244 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes | SRRA | Series B Warrants | I | 13,20 | -374.962 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes (4), | SRRA | Common Stock | I | 13,2000 | 56.244 | 742 | 226.704 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes | SRRA | Common Stock | I | 13,2000 | 56.244 | 742 | 226.704 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Ashiya Mona See footnotes (4), | SRRA | Common Stock | I | 13,2000 | 374.962 | 4.949 | 1.511.362 | ||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC | SRRA | Series B Warrants | I | 13,20 | -56.244 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC | SRRA | Series B Warrants | I | 13,20 | -56.244 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC | SRRA | Series B Warrants | I | 13,20 | -374.962 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC | SRRA | Common Stock | I | 13,2000 | 56.244 | 742 | 226.704 | ||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC See footnote (4), | SRRA | Common Stock | I | 13,2000 | 56.244 | 742 | 226.704 | ||||
| 2022-01-28 | 2022-01-26 | 4 | ORBIMED ADVISORS LLC See footnote (4), | SRRA | Common Stock | I | 13,2000 | 374.962 | 4.949 | 1.511.362 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P. | SRRA | Series B Warrant (Right to Purchase ) | I | 13,20 | 13,2000 | -324.740 | -4.287 | 0 | |||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Opportunity Fund, L.P. | SRRA | Series B Warrant (Right to Purchase ) | I | 13,20 | 13,2000 | -1.455.384 | -19.211 | 0 | |||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Series B Warrant (Right to Purchase ) | I | 13,20 | 13,2000 | -75.749 | -1.000 | 0 | |||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P. | SRRA | Common Stock | I | 13,2000 | 107.164 | 1.415 | 431.947 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Opportunity Fund, L.P. | SRRA | Common Stock | I | 13,2000 | 480.277 | 6.340 | 1.935.853 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 13,2000 | 24.996 | 330 | 161.712 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Aggarwal Gaurav By Vivo Opportunity Fund, L.P. | SRRA | Series B Warrant (Right to Purchase) | I | 13,20 | 13,2000 | -1.455.384 | -19.211 | 0 | |||
| 2022-01-28 | 2022-01-26 | 4 | Aggarwal Gaurav By Vivo Opportunity Fund, L.P. | SRRA | Common Stock | I | 13,2000 | 480.277 | 6.340 | 1.935.853 | ||||
| 2022-01-28 | 2022-01-28 | 4 | Klencke Barbara | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-28 | 4 | Kowalski Mark | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-28 | 4 | Norrett Kevin | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-28 | 4 | DILLY STEPHEN GEORGE | SRRA | Stock Option (Right to Buy) | D | 12,15 | 65.000 | 65.000 | |||||
| 2022-01-28 | 2022-01-28 | 4 | Jagpal Sukhi | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-28 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 13,04 | 2.000 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 29,0000 | -2.000 | -58 | 0 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Thomson Mary Christina | SRRA | Common Stock | D | 13,0400 | 2.000 | 26 | 2.000 | ||||
| 2022-01-28 | 2022-01-28 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,15 | 12.250 | 12.250 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 12,05 | 5.000 | 0 | |||||
| 2022-01-28 | 2022-01-26 | 4 | Turner William D. | SRRA | Common Stock | D | 27,0500 | -5.000 | -135 | 0 | ||||
| 2022-01-28 | 2022-01-26 | 4 | Turner William D. | SRRA | Common Stock | D | 12,0500 | 5.000 | 60 | 5.000 | ||||
| 2022-01-27 | 2022-01-25 | 4 | Longitude Capital Partners III, LLC | SRRA | Series B Warrants | I | 13,20 | 13,2000 | -1.477.125 | -19.498 | 0 | |||
| 2022-01-27 | 2022-01-25 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 13,2000 | 487.451 | 6.434 | 1.964.771 | ||||
| 2022-01-27 | 2022-01-25 | 4 | Richardson Joshua By Longitude Venture Partners III, L.P. | SRRA | Series B Warrants | I | 13,20 | 13,2000 | -1.477.125 | -19.498 | 0 | |||
| 2022-01-27 | 2022-01-25 | 4 | Richardson Joshua By Longitude Venture Partners III, L.P. | SRRA | Common Stock | I | 13,2000 | 487.451 | 6.434 | 1.964.771 | ||||
| 2021-11-24 | 2021-11-24 | 4 | Collard Craig A | SRRA | Common Stock | D | 23,0850 | 7.899 | 182 | 13.500 | ||||
| 2021-11-24 | 2021-11-23 | 4 | Collard Craig A | SRRA | Common Stock | D | 22,9450 | 5.601 | 129 | 5.601 | ||||
| 2021-11-05 | 3 | Abingworth LLP | SRRA | Common Stock, $0.001 par value | I | 878.656 | ||||||||
| 2021-06-28 | 2021-03-15 | 4 | Thomson Mary Christina | SRRA | Stock Option (Right to Buy) | D | 16,73 | 12.900 | 12.900 | |||||
| 2021-06-28 | 2020-07-28 | 4 | Thomson Mary Christina | SRRA | Stock option (right to buy) | D | 13,04 | 100.000 | 100.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Cooper Jeffrey H | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Collard Craig A | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Pelzer Robert | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Ashiya Mona | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Allen Andrew R | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Aggarwal Gaurav | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Sinclair Andrew | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Richardson Joshua | SRRA | Stock Option (Right To Buy) | D | 18,11 | 6.000 | 6.000 | |||||
| 2021-06-04 | 2021-06-02 | 4 | Oliger Christy J. | SRRA | Stock Option (right to buy) | D | 17,76 | 18.000 | 18.000 | |||||
| 2021-06-04 | 2021-06-02 | 4 | Erbez Georgia | SRRA | Stock Option (right to buy) | D | 17,76 | 18.000 | 18.000 | |||||
| 2021-05-20 | 2021-05-19 | 4 | DILLY STEPHEN GEORGE | SRRA | Common Stock | D | 17,8300 | 5.000 | 89 | 5.000 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Turner William D. | SRRA | Stock Option (Right to Buy) | D | 16,73 | 12.300 | 12.300 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Thomson Christina | SRRA | Stock Option (Right to Buy) | D | 16,73 | 12.900 | 12.900 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Norrett Kevin | SRRA | Stock Option (Right to Buy) | D | 16,73 | 11.700 | 11.700 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Kowalski Mark | SRRA | Stock Option (Right to Buy) | D | 16,73 | 30.000 | 30.000 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Jagpal Sukhi | SRRA | Stock Option (Right to Buy) | D | 16,73 | 30.000 | 30.000 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Klencke Barbara | SRRA | Stock Option (Right to Buy) | D | 16,73 | 30.000 | 30.000 | |||||
| 2021-03-17 | 2021-03-15 | 4 | DILLY STEPHEN GEORGE | SRRA | Stock Option (Right to Buy) | D | 16,73 | 92.000 | 92.000 | |||||
| 2020-08-18 | 2020-08-18 | 4 | Klencke Barbara By spouse | SRRA | Common Stock | I | 12,2519 | 3.325 | 41 | 5.000 | ||||
| 2020-08-18 | 2020-08-18 | 4 | Klencke Barbara | SRRA | Common Stock | D | 12,2201 | 5.950 | 73 | 10.000 | ||||
| 2020-08-12 | 2020-08-12 | 4 | Jagpal Sukhi | SRRA | Stock Option (right to buy) | D | 12,15 | 5.887 | 5.887 | |||||
| 2020-08-12 | 2020-08-12 | 4 | Kowalski Mark | SRRA | Stock Option (right to buy) | D | 12,15 | 24.970 | 24.970 | |||||
| 2020-08-11 | 2020-08-10 | 4 | Norrett Kevin | SRRA | Stock option (right to buy) | D | 12,05 | 100.000 | 100.000 | |||||
| 2020-08-06 | 2020-08-04 | 4 | Turner William D. | SRRA | Stock option (right to buy) | D | 12,05 | 100.000 | 100.000 | |||||
| 2020-07-29 | 2020-07-28 | 4 | Thomson Christina | SRRA | Stock option (right to buy) | D | 13,04 | 100.000 | 100.000 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Aggarwal Gaurav | SRRA | Stock Option (right to buy) | D | 13,98 | 6.874 | 6.874 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Allen Andrew R | SRRA | Stock Option (right to buy) | D | 13,98 | 12.030 | 12.030 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Ashiya Mona | SRRA | Stock Option (right to buy) | D | 13,98 | 6.874 | 6.874 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Cooper Jeffrey H | SRRA | Stock Option (right to buy) | D | 13,98 | 18.061 | 18.061 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Pelzer Robert | SRRA | Stock Option (right to buy) | D | 13,98 | 16.686 | 16.686 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Richardson Joshua | SRRA | Stock Option (right to buy) | D | 13,98 | 6.874 | 6.874 | |||||
| 2020-06-10 | 2020-06-09 | 4 | Sinclair Andrew | SRRA | Stock Option (right to buy | D | 13,98 | 6.874 | 6.874 | |||||
| 2020-06-02 | 2020-06-01 | 4 | DILLY STEPHEN GEORGE | SRRA | Stock Option (right to buy) | D | 14,03 | 520.000 | 520.000 | |||||
| 2020-05-29 | 2020-05-28 | 4 | Collard Craig A | SRRA | Stock Option (right to buy) | D | 13,88 | 10.000 | 10.000 | |||||
| 2020-02-27 | 2020-02-25 | 4 | Glover Nicholas | SRRA | Stock Option (right to buy) | D | 13,31 | 359.158 | 359.158 | |||||
| 2020-02-27 | 2020-02-25 | 4 | Jagpal Sukhi | SRRA | Stock Option (right to buy) | D | 13,31 | 94.113 | 94.113 | |||||
| 2020-02-27 | 2020-02-25 | 4 | Klencke Barbara | SRRA | Stock Option (right to buy) | D | 13,31 | 167.091 | 167.091 | |||||
| 2020-02-27 | 2020-02-25 | 4 | Kowalski Mark | SRRA | Stock Option (right to buy) | D | 13,31 | 75.030 | 75.030 | |||||
| 2020-02-03 | 2020-01-29 | 4/A | Sinclair Andrew See footnotes | SRRA | Series A Convertible Voting Preferred Stock | I | -11.500 | 0 | ||||||
| 2020-02-03 | 2020-01-29 | 4/A | Sinclair Andrew See footnotes | SRRA | Common Stock | I | 871.240 | 876.656 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | ORBIMED ADVISORS LLC See footnotes | SRRA | Series A Convertible Voting Preferred Stock | I | -19.500 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | ORBIMED ADVISORS LLC See footnotes | SRRA | Common Stock | I | 1.477.320 | 1.477.320 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Aggarwal Gaurav By Vivo Opportunity Fund, LP | SRRA | Series A Convertible Voting Preferred Stock | I | -19.213 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Aggarwal Gaurav By Vivo Opportunity Fund, LP | SRRA | Common Stock | I | 1.455.576 | 1.455.576 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Ashiya Mona See footnotes | SRRA | Series A Convertible Voting Preferred Stock | I | -19.500 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Ashiya Mona See footnotes | SRRA | Common Stock | I | 1.477.320 | 1.477.320 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Richardson Joshua By Longitude Venture Partners III, L.P. | SRRA | Series A Convertible Voting Preferred Stock | I | -19.500 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Richardson Joshua By Longitude Venture Partners III, L.P. | SRRA | Common Stock | I | 1.477.320 | 1.477.320 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Longitude Capital Partners III, LLC | SRRA | Series A Convertible Voting Preferred Stock | I | -19.500 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Longitude Capital Partners III, LLC | SRRA | Common Stock | I | 1.477.320 | 1.477.320 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P. | SRRA | Series A Convertible Voting Preferred Stock | I | -4.287 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P. | SRRA | Series A Convertible Voting Preferred Stock | I | -19.213 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Series A Convertible Voting Preferred Stock | I | -1.000 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P. | SRRA | Common Stock | I | 324.783 | 324.783 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P. | SRRA | Common Stock | I | 1.455.576 | 1.455.576 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 75.759 | 136.715 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Sinclair Andrew See footnotes | SRRA | Series A Convertible Voting Preferred Stock | I | -11.500 | 0 | ||||||
| 2020-01-31 | 2020-01-29 | 4 | Sinclair Andrew See footnotes | SRRA | Common Stock | I | 871.125 | 876.542 | ||||||
| 2019-12-03 | 2019-11-29 | 4 | Sinclair Andrew | SRRA | Stock Option (right to buy) | D | 0,35 | 60.000 | 60.000 | |||||
| 2019-12-03 | 2019-11-29 | 4 | Aggarwal Gaurav | SRRA | Stock Option (Right to Buy) | D | 0,35 | 60.000 | 60.000 | |||||
| 2019-12-03 | 2019-11-29 | 4 | Ashiya Mona | SRRA | Stock Option (Right to Buy) | D | 0,35 | 60.000 | 60.000 | |||||
| 2019-12-03 | 2019-11-29 | 4 | Richardson Joshua | SRRA | Stock Option (Right to Buy) | D | 0,35 | 60.000 | 60.000 | |||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-12-02 | 3 | Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P. | SRRA | Common Stock | I | 4.876.540 | ||||||||
| 2019-11-26 | 3 | Sinclair Andrew See Footnotes | SRRA | Common Stock, $0.001 par value | I | 433.334 | ||||||||
| 2019-11-26 | 3 | Sinclair Andrew See Footnotes | SRRA | Common Stock, $0.001 par value | I | 433.334 | ||||||||
| 2019-11-26 | 3 | Sinclair Andrew See Footnotes | SRRA | Common Stock, $0.001 par value | I | 433.334 | ||||||||
| 2019-08-26 | 2019-08-23 | 4 | Klencke Barbara | SRRA | Common Stock | D | 0,4387 | 108.000 | 47 | 162.000 | ||||
| 2019-08-26 | 2019-08-22 | 4 | Klencke Barbara | SRRA | Common Stock | D | 0,4499 | 54.000 | 24 | 54.000 | ||||
| 2019-08-26 | 2019-08-22 | 4 | Klencke Barbara By spouse | SRRA | Common Stock | I | 0,4323 | 67.000 | 29 | 67.000 | ||||
| 2019-06-12 | 2019-06-11 | 4 | Cooper Jeffrey H | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | ESTES DANIEL | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Nguyen Tran | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | ONETTO NICOLE | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Parfet Donald R | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Pelzer Robert | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Allen Andrew R | SRRA | Stock Option (right to buy) | D | 0,66 | 30.000 | 30.000 | |||||
| 2019-03-05 | 2019-03-04 | 4 | Glover Nicholas | SRRA | Stock Option (right to buy) | D | 1,96 | 607.500 | 607.500 | |||||
| 2019-03-05 | 2019-03-04 | 4 | Hassig Christian | SRRA | Stock Option (right to buy) | D | 1,96 | 155.000 | 155.000 | |||||
| 2019-03-05 | 2019-03-04 | 4 | Jagpal Sukhi | SRRA | Stock Option (right to buy) | D | 1,96 | 200.000 | 200.000 | |||||
| 2019-03-05 | 2019-03-04 | 4 | Klencke Barbara | SRRA | Stock Option (right to buy) | D | 1,96 | 200.000 | 200.000 | |||||
| 2019-03-05 | 2019-03-04 | 4 | Kowalski Mark | SRRA | Stock Option (right to buy) | D | 1,96 | 200.000 | 200.000 | |||||
| 2018-12-11 | 2018-12-10 | 4 | Allen Andrew R | SRRA | Common Stock | D | 1,6400 | 66.000 | 108 | 66.000 | ||||
| 2018-06-14 | 2018-06-12 | 4 | Pelzer Robert | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | ESTES DANIEL | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Allen Andrew R | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Cooper Jeffrey H | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Nguyen Tran | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | ONETTO NICOLE | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-06-14 | 2018-06-12 | 4 | Parfet Donald R | SRRA | Stock Option (right to buy) | D | 3,27 | 25.000 | 25.000 | |||||
| 2018-03-07 | 2018-03-06 | 4 | Glover Nicholas | SRRA | Stock Option (right to buy) | D | 2,36 | 562.780 | 562.780 | |||||
| 2018-03-07 | 2018-03-06 | 4 | Hassig Christian | SRRA | Stock Option (right to buy) | D | 2,36 | 205.180 | 205.180 | |||||
| 2018-03-07 | 2018-03-06 | 4 | Jagpal Sukhi | SRRA | Stock Option (right to buy) | D | 2,36 | 180.360 | 180.360 | |||||
| 2018-03-07 | 2018-03-06 | 4 | Klencke Barbara | SRRA | Stock Option (right to buy) | D | 2,36 | 180.360 | 180.360 | |||||
| 2018-03-07 | 2018-03-06 | 4 | Kowalski Mark | SRRA | Stock Option (right to buy) | D | 2,36 | 155.000 | 155.000 | |||||
| 2018-03-07 | 2018-03-06 | 4 | You Angie | SRRA | Stock Option (right to buy) | D | 2,36 | 180.360 | 180.360 | |||||
| 2018-01-08 | 2018-01-04 | 4 | Parfet Donald R | SRRA | Common Stock | D | 1.380 | 77.235 | ||||||
| 2018-01-08 | 2018-01-04 | 4 | Parfet Donald R Apjohn Ventures, LLC | SRRA | Common Stock | I | -2.760 | 0 | ||||||
| 2018-01-08 | 2018-01-04 | 4 | Parfet Donald R Apjohn Ventures, LLC | SRRA | Common Stock | I | 1.068 | 2.760 | ||||||
| 2018-01-08 | 2018-01-04 | 4 | Parfet Donald R Apjohn Ventures, LLC | SRRA | Common Stock | I | 1.692 | 1.692 | ||||||
| 2018-01-08 | 2018-01-04 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | SRRA | Common Stock | I | 3.383 | 390.913 | ||||||
| 2017-11-13 | 2017-11-10 | 4 | Allen Andrew R | SRRA | Stock Option (Right to Buy) | D | 1,92 | 50.000 | 50.000 | |||||
| 2017-10-25 | 3 | Allen Andrew R | SRRA | No securities beneficially owned. | D | 0 | ||||||||
| 2017-06-14 | 2017-06-13 | 4 | Cooper Jeffrey H | SRRA | Stock Option (right to buy) | D | 1,13 | 25.000 | 25.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | Nguyen Tran | SRRA | Stock Option (right to buy) | D | 1,13 | 25.000 | 25.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | ONETTO NICOLE | SRRA | Stock Option (right to buy) | D | 1,13 | 25.000 | 25.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | Parfet Donald R | SRRA | Stock Option (right to buy) | D | 1,13 | 25.000 | 25.000 | |||||
| 2017-06-14 | 2017-06-13 | 4 | Pelzer Robert | SRRA | Stock Option (right to buy) | D | 1,13 | 25.000 | 25.000 | |||||
| 2017-05-30 | 2017-05-25 | 4 | ESTES DANIEL | SRRA | Stock Option (Right to Buy) | D | 1,20 | 50.000 | 50.000 | |||||
| 2017-04-11 | 3 | ESTES DANIEL | SRRA | No securities beneficially owned | D | 0 | ||||||||
| 2017-03-09 | 2017-03-08 | 4 | You Angie | SRRA | Common Stock | D | 1,4300 | 30.000 | 43 | 133.252 | ||||
| 2017-03-08 | 2017-03-06 | 4 | You Angie | SRRA | Stock Option (right to buy) | D | 1,45 | 70.000 | 70.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Jagpal Sukhi | SRRA | Stock Option (right to buy) | D | 1,45 | 70.000 | 70.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Klencke Barbara | SRRA | Stock Option (right to buy) | D | 1,45 | 70.000 | 70.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Glover Nicholas | SRRA | Stock Option (right to buy) | D | 1,45 | 195.000 | 195.000 | |||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 14.038.047 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-24 | 3 | Heron Patrick J | SRRA | Common Stock | D | 10.298.316 | ||||||||
| 2017-02-16 | 2017-02-14 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | SRRA | Common Stock | I | 1,3500 | 5.925.926 | 8.000 | 5.925.926 | ||||
| 2017-01-04 | 3 | Kowalski Mark | DNAI | No securities beneficially held | D | 0 | ||||||||
| 2017-01-04 | 2017-01-03 | 4 | Kowalski Mark | DNAI | Stock Option (right to buy Class A Common Stock) | D | 1,54 | 300.000 | 300.000 | |||||
| 2016-11-10 | 2016-11-08 | 4 | Parfet Donald R | DNAI | Common Stock | D | 2.403 | 75.855 | ||||||
| 2016-11-10 | 2016-11-08 | 4 | Parfet Donald R Apjohn Ventures, LLC | DNAI | Common Stock | I | -4.806 | 0 | ||||||
| 2016-11-10 | 2016-11-08 | 4 | Parfet Donald R Apjohn Ventures, LLC | DNAI | Common Stock | I | 1.423 | 4.806 | ||||||
| 2016-11-10 | 2016-11-08 | 4 | Parfet Donald R Apjohn Ventures, LLC | DNAI | Common Stock | I | 3.383 | 3.383 | ||||||
| 2016-11-10 | 2016-11-08 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 6.767 | 387.530 | ||||||
| 2016-10-04 | 2016-09-30 | 4 | Jagpal Sukhi | DNAI | Stock Option (right to buy) | D | 1,82 | 168.000 | 168.000 | |||||
| 2016-10-04 | 2016-09-30 | 4 | Glover Nicholas | DNAI | Stock Option (right to buy) | D | 1,82 | 500.000 | 500.000 | |||||
| 2016-10-04 | 2016-09-30 | 4 | Klencke Barbara | DNAI | Stock Option (right to buy) | D | 1,82 | 456.000 | 456.000 | |||||
| 2016-10-04 | 2016-09-30 | 4 | You Angie | DNAI | Stock Option (right to buy) | D | 1,82 | 200.000 | 200.000 | |||||
| 2016-09-30 | 2016-09-29 | 4 | Parfet Donald R | DNAI | Common Stock | D | 1.202 | 73.452 | ||||||
| 2016-09-30 | 2016-09-29 | 4 | Parfet Donald R By Apjohn Ventures, LLC | DNAI | Common Stock | I | -2.403 | 0 | ||||||
| 2016-09-30 | 2016-09-29 | 4 | Parfet Donald R By Apjohn Ventures, LLC | DNAI | Common Stock | I | 711 | 2.403 | ||||||
| 2016-09-30 | 2016-09-29 | 4 | Parfet Donald R By Apjohn Ventures, LLC | DNAI | Common Stock | I | 1.692 | 1.692 | ||||||
| 2016-09-30 | 2016-09-29 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 3.384 | 380.763 | ||||||
| 2016-06-20 | 2016-06-16 | 4 | ONETTO NICOLE | DNAI | Stock Option (right to buy) | D | 2,06 | 38.835 | 38.835 | |||||
| 2016-06-20 | 2016-06-16 | 4 | Pelzer Robert | DNAI | Stock Option (right to buy) | D | 2,06 | 38.835 | 38.835 | |||||
| 2016-06-20 | 2016-06-16 | 4 | Parfet Donald R | DNAI | Stock Option (right to buy) | D | 2,06 | 38.835 | 38.835 | |||||
| 2016-06-20 | 2016-06-16 | 4 | Topper James N | DNAI | Stock Option (right to buy) | D | 2,06 | 38.835 | 38.835 | |||||
| 2016-06-13 | 2016-06-09 | 4 | Cooper Jeffrey H | DNAI | Stock Option (right to buy) | D | 2,06 | 77.670 | 77.670 | |||||
| 2016-06-13 | 2016-06-09 | 4 | Nguyen Tran | DNAI | Stock Option (right to buy) | D | 2,06 | 77.670 | 77.670 | |||||
| 2016-05-17 | 2016-05-13 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 3.204 | 377.379 | ||||||
| 2016-03-24 | 3 | Nguyen Tran | DNAI | No securities beneficially held | D | 0 | ||||||||
| 2016-03-24 | 3 | Cooper Jeffrey H | DNAI | No securities beneficially held | D | 0 | ||||||||
| 2016-03-24 | 2016-03-22 | 4 | Chapman Wendy | DNAI | Stock Option (right to buy) | D | 0,97 | -3.000 | 76.248 | |||||
| 2016-03-24 | 2016-03-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 7,0078 | -3.000 | -21 | 0 | ||||
| 2016-03-24 | 2016-03-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 0,9690 | 3.000 | 3 | 3.000 | ||||
| 2016-03-10 | 2016-03-08 | 4 | Messmann Richard A | DNAI | Stock Option (right to buy) | D | 6,58 | 25.000 | 25.000 | |||||
| 2016-03-10 | 2016-03-08 | 4 | Lovejoy Chandra D | DNAI | Stock Option (right to buy) | D | 6,58 | 31.000 | 31.000 | |||||
| 2016-03-10 | 2016-03-08 | 4 | Jagpal Sukhi | DNAI | Stock Option (right to buy) | D | 6,58 | 48.750 | 48.750 | |||||
| 2016-03-10 | 2016-03-08 | 4 | Glover Nicholas | DNAI | Stock Option (right to buy) | D | 6,58 | 161.250 | 161.250 | |||||
| 2016-03-10 | 2016-03-08 | 4 | Klencke Barbara | DNAI | Stock Option (right to buy) | D | 6,58 | 82.500 | 82.500 | |||||
| 2016-03-10 | 2016-03-08 | 4 | Chapman Wendy | DNAI | Stock Option (right to buy) | D | 6,58 | 25.000 | 25.000 | |||||
| 2016-03-10 | 2016-03-08 | 4 | You Angie | DNAI | Stock Option (right to buy) | D | 6,58 | 75.000 | 75.000 | |||||
| 2016-02-24 | 2016-02-22 | 4 | Chapman Wendy | DNAI | Stock Option (right to buy) | D | 0,97 | -3.000 | 79.248 | |||||
| 2016-02-24 | 2016-02-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 7,0600 | -3.000 | -21 | 0 | ||||
| 2016-02-24 | 2016-02-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 0,9690 | 3.000 | 3 | 3.000 | ||||
| 2016-01-25 | 2016-01-22 | 4 | Chapman Wendy | DNAI | Stock Option (right to buy) | D | 0,97 | -5.000 | 82.248 | |||||
| 2016-01-25 | 2016-01-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 9,3946 | -5.000 | -47 | 0 | ||||
| 2016-01-25 | 2016-01-22 | 4 | Chapman Wendy | DNAI | Common Stock | D | 0,9690 | 5.000 | 5 | 5.000 | ||||
| 2016-01-22 | 2016-01-22 | 4 | Rodigueza Wendi | DNAI | Common Stock | D | 9,6600 | -1.000 | -10 | 156.276 | ||||
| 2016-01-22 | 2016-01-21 | 4 | Rodigueza Wendi | DNAI | Common Stock | D | 10,3230 | -1.000 | -10 | 157.276 | ||||
| 2016-01-22 | 2016-01-20 | 4 | Rodigueza Wendi | DNAI | Common Stock | D | 9,5900 | -1.000 | -10 | 158.276 | ||||
| 2016-01-19 | 2016-01-15 | 4 | Glover Nicholas | DNAI | Stock Option (right to buy) | D | 0,97 | -5.000 | 864.219 | |||||
| 2016-01-19 | 2016-01-15 | 4 | Glover Nicholas | DNAI | Common Stock | D | 10,0446 | -5.000 | -50 | 0 | ||||
| 2016-01-19 | 2016-01-15 | 4 | Glover Nicholas | DNAI | Common Stock | D | 0,9690 | 5.000 | 5 | 5.000 | ||||
| 2016-01-14 | 2016-01-12 | 4 | Lovejoy Chandra D | DNAI | Stock Option (right to buy) | D | 0,97 | -7.551 | 46.140 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Lovejoy Chandra D | DNAI | Common Stock | D | 11,9282 | -5.562 | -66 | 0 | ||||
| 2016-01-14 | 2016-01-12 | 4 | Lovejoy Chandra D | DNAI | Common Stock | D | 11,0628 | -15.411 | -170 | 5.562 | ||||
| 2016-01-14 | 2016-01-12 | 4 | Lovejoy Chandra D | DNAI | Common Stock | D | 0,9690 | 7.551 | 7 | 20.973 | ||||
| 2015-12-02 | 3 | Anderson Keith Edward | DNAI | No securities are beneficially owned | D | 0 | ||||||||
| 2015-12-02 | 2015-12-01 | 4 | Anderson Keith Edward | DNAI | Stock Option (right to buy) | D | 18,33 | 100.000 | 100.000 | |||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Series D Preferred Stock | I | -287.631 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Series C Preferred Stock | I | -471.242 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Series C Preferred Stock | I | -38.824 | 471.242 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Series C Preferred Stock | I | 126.558 | 510.066 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Series C Preferred Stock Warrant (right to buy) | I | 5,2150 | -126.558 | -660 | 0 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Common Stock | I | 5,2150 | 39.889 | 208 | 798.762 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Common Stock | I | 287.631 | 758.873 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Vitangcol Alvin By Capital Midwest Fund II, L.P. | DNAI | Common Stock | I | 471.242 | 471.242 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Topper James N By Frazier Healthcare VI, L.P. | DNAI | Series D Preferred Stock | I | -1.869.606 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Topper James N By Frazier Healthcare VI, L.P. | DNAI | Common Stock | I | 17,0000 | 220.000 | 3.740 | 2.186.195 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Topper James N By Frazier Healthcare VI, L.P. | DNAI | Common Stock | I | 5,2150 | 96.589 | 504 | 1.966.195 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Topper James N By Frazier Healthcare VI, L.P. | DNAI | Common Stock | I | 1.869.606 | 1.869.606 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Thompson Peter A. See Footnotes | DNAI | Series D Preferred Stock | I | -1.725.790 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Thompson Peter A. See Footnotes | DNAI | Common Stock | I | 17,0000 | 175.000 | 2.975 | 1.989.949 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Thompson Peter A. See Footnotes | DNAI | Common Stock | I | 5,2150 | 89.159 | 465 | 1.814.949 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Thompson Peter A. See Footnotes | DNAI | Common Stock | I | 1.725.790 | 1.725.790 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Rodigueza Wendi | DNAI | Series B-1 Preferred Stock | D | -1.966 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Rodigueza Wendi | DNAI | Common Stock | D | 1.966 | 159.276 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Palmero Group LLC | DNAI | Series C Preferred Stock | I | -13.130 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Palmero Group LLC | DNAI | Series A Preferred Stock | I | -46.034 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Series B-1 Preferred Stock | I | -142.422 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Series B Preferred Stock | I | -189.933 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Series A Preferred Stock | I | -306 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Series C Preferred Stock | I | -65.938 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Series B-1 Preferred Stock | I | -121.242 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Series B Preferred Stock | I | -23.944 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By wife | DNAI | Series A Preferred Stock | I | -4.415 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series C Preferred Stock | I | -24.277 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series C Preferred Stock | I | -221 | 24.277 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series C Preferred Stock | I | 719 | 24.498 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series C Preferred Stock Warrant (right to buy) | I | 5,2150 | -719 | -4 | 0 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock | I | -516.203 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock | I | -2.941 | 516.203 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock | I | 6.711 | 519.144 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock Warrant (right to buy) | I | 7,4500 | -6.711 | -50 | 0 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock | I | -40.729 | 512.433 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R y Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock | I | 265.536 | 553.162 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B-1 Preferred Stock Warrant (right to buy) | I | 2,6080 | -265.536 | -693 | 0 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series B Preferred Stock | I | -153.485 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Series A Preferred Stock | I | -26.728 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Series D Preferred Stock | I | -11.505 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Series C Preferred Stock | I | -59.225 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Series B-1 Preferred Stock | I | -67.112 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Group, LLC | DNAI | Series A Preferred Stock | I | -307 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Palmero Group LLC | DNAI | Common Stock | I | 5,2150 | 819 | 4 | 65.779 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Palmero Group LLC | DNAI | Common Stock | I | 13.130 | 64.960 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Palmero Group LLC | DNAI | Common Stock | I | 51.830 | 51.830 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 142.422 | 353.802 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 211.036 | 211.380 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006 | DNAI | Common Stock | I | 344 | 344 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Common Stock | I | 5,2150 | 4.119 | 21 | 217.903 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Common Stock | I | 65.938 | 213.784 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Common Stock | I | 121.242 | 147.846 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006 | DNAI | Common Stock | I | 26.604 | 26.604 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By wife | DNAI | Common Stock | I | 4.970 | 4.970 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 5,2150 | 1.552 | 8 | 770.045 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 24.277 | 768.493 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 516.203 | 744.216 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 170.538 | 228.013 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 30.093 | 57.475 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Common Stock | I | 5,2150 | 4.413 | 23 | 142.255 | ||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Common Stock | I | 11.505 | 137.842 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Common Stock | I | 59.225 | 126.337 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Ventures Annex Fund LP | DNAI | Common Stock | I | 67.112 | 67.112 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | Parfet Donald R By Apjohn Group, LLC | DNAI | Common Stock | I | 345 | 589 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Series D Preferred Stock | I | -44.991 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | DNAI | Series D Preferred Stock | I | -2.064.308 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 17,0000 | 4.693 | 80 | 2.438.270 | ||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 17,0000 | 215.307 | 3.660 | 2.433.577 | ||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 5,2150 | 2.324 | 12 | 2.218.270 | ||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 5,2150 | 106.647 | 556 | 2.215.946 | ||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 44.991 | 2.109.299 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 2.064.308 | 2.064.308 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Series D Preferred Stock | I | -44.991 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures Fund VII, L.P. | DNAI | Series D Preferred Stock | I | -2.064.308 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 17,0000 | 4.693 | 80 | 2.438.270 | ||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 17,0000 | 215.307 | 3.660 | 2.433.577 | ||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 5,2150 | 2.324 | 12 | 2.218.270 | ||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 5,2150 | 106.647 | 556 | 2.215.946 | ||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P. | DNAI | Common Stock | I | 44.991 | 2.109.299 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | CHA ALBERT By Vivo Ventures Fund VII, L.P. | DNAI | Common Stock | I | 2.064.308 | 2.064.308 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | ORBIMED ADVISORS LLC See Footnotes | DNAI | Series D Preferred Stock | I | -1.725.790 | 0 | ||||||
| 2015-07-21 | 2015-07-21 | 4 | ORBIMED ADVISORS LLC See Footnotes | DNAI | Common Stock | I | 17,0000 | 175.000 | 2.975 | 1.989.949 | ||||
| 2015-07-21 | 2015-07-21 | 4 | ORBIMED ADVISORS LLC See Footnotes | DNAI | Common Stock | I | 5,2150 | 89.159 | 465 | 1.814.949 | ||||
| 2015-07-21 | 2015-07-21 | 4 | ORBIMED ADVISORS LLC See Footnotes | DNAI | Common Stock | I | 1.725.790 | 1.725.790 | ||||||
| 2015-07-15 | 3 | You Angie | DNAI | Common Stock | D | 206.504 | ||||||||
| 2015-07-15 | 3 | You Angie | DNAI | Common Stock | D | 206.504 | ||||||||
| 2015-07-15 | 3 | Rodigueza Wendi | DNAI | Common Stock | D | 314.620 | ||||||||
| 2015-07-15 | 3 | Rodigueza Wendi | DNAI | Common Stock | D | 314.620 | ||||||||
| 2015-07-15 | 3 | Messmann Richard A | DNAI | Common Stock | D | 80.104 | ||||||||
| 2015-07-15 | 3 | Messmann Richard A | DNAI | Common Stock | D | 80.104 | ||||||||
| 2015-07-15 | 3 | Lovejoy Chandra D | DNAI | Common Stock | D | 26.844 | ||||||||
| 2015-07-15 | 3 | Lovejoy Chandra D | DNAI | Common Stock | D | 26.844 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R By Apjohn Group, LLC | DNAI | Common Stock | I | 97.718 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 124.856 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R By Apjohn Ventures Fund, LP | DNAI | Common Stock | I | 124.856 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R By Apjohn Group, LLC | DNAI | Common Stock | I | 97.718 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R | DNAI | Common Stock | D | 167.322 | ||||||||
| 2015-07-15 | 3 | Parfet Donald R | DNAI | Common Stock | D | 167.322 |
